about
The current state of eukaryotic DNA base damage and repairStructure-function studies of DNA polymerase λAn overview of Y-Family DNA polymerases and a case study of human DNA polymerase ηPhosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.RB69 DNA polymerase structure, kinetics, and fidelity.Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q.Structural basis for the D-stereoselectivity of human DNA polymerase β.Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.Ultrafast water dynamics at the interface of the polymerase-DNA binding complexStructural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity.Substrate-induced DNA polymerase β activation.Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotideEffects of DNA3'pp5'G capping on 3' end repair reactions and of an embedded pyrophosphate-linked guanylate on ribonucleotide surveillance.Genetic evidence that both dNTP-stabilized and strand slippage mechanisms may dictate DNA polymerase errors within mononucleotide microsatellites.New structural snapshots provide molecular insights into the mechanism of high fidelity DNA synthesis.Bypass of a 5',8-cyclopurine-2'-deoxynucleoside by DNA polymerase β during DNA replication and base excision repair leads to nucleotide misinsertions and DNA strand breaks.Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse.The K167I variant of DNA polymerase β that is found in Esophageal Carcinoma patients impairs polymerase activity and BER.Linking DNA polymerase theta structure and function in health and diseaseInsertion of oxidized nucleotide triggers rapid DNA polymerase openingProduction, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements.Applications of quantum mechanical/molecular mechanical methods to the chemical insertion step of DNA and RNA polymerization.Time-lapse crystallography snapshots of a double-strand break repair polymerase in actionDifferent Divalent Cations Alter the Kinetics and Fidelity of DNA Polymerases.Unencumbered Pol β lyase activity in nucleosome core particles.Development of a Cell-Based Assay for Measuring Base Excision Repair Responses.A single-molecule FRET sensor for monitoring DNA synthesis in real time.Modulating the DNA polymerase β reaction equilibrium to dissect the reverse reaction.Pyrimidine Nucleosides with a Reactive (β-Chlorovinyl)sulfone or (β-Keto)sulfone Group at the C5 Position, Their Reactions with Nucleophiles and Electrophiles, and Their Polymerase-Catalyzed Incorporation into DNA.The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent trinucleotide repeat instability
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure and mechanism of DNA polymerase β
@ast
Structure and mechanism of DNA polymerase β
@en
Structure and mechanism of DNA polymerase β
@nl
type
label
Structure and mechanism of DNA polymerase β
@ast
Structure and mechanism of DNA polymerase β
@en
Structure and mechanism of DNA polymerase β
@nl
prefLabel
Structure and mechanism of DNA polymerase β
@ast
Structure and mechanism of DNA polymerase β
@en
Structure and mechanism of DNA polymerase β
@nl
P2860
P3181
P356
P1433
P1476
Structure and mechanism of DNA polymerase β
@en
P2093
William A Beard
P2860
P304
P3181
P356
10.1021/BI500139H
P407
P577
2014-05-06T00:00:00Z