The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains
about
Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteinsA crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.Signal-dependent membrane targeting by pleckstrin homology (PH) domainsThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseStructural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathwayRole of the histone domain in the autoinhibition and activation of the Ras activator Son of SevenlessThe solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunitsStructure and mutagenesis of the Dbl homology domainLoss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targetingMultifunctional roles for the PH domain of Dbs in regulating Rho GTPase activationModular PH and C2 domains in membrane attachment and other functions.Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless.Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4.Signaling to the Rho GTPases: networking with the DH domain.SOS1 mutations in Noonan syndrome: molecular spectrum, structural insights on pathogenic effects, and genotype-phenotype correlationsMembrane-dependent signal integration by the Ras activator Son of sevenless.Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives.Conditional peripheral membrane proteins: facing up to limited specificity.Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.A central role for phosphatidic acid as a lipid mediator of regulated exocytosis in apicomplexa.Differential motility of p190bcr-abl- and p210bcr-abl-expressing cells: respective roles of Vav and Bcr-Abl GEFs.The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity.Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BPCritical role of the pleckstrin homology domain in Dbs signaling and growth regulation.Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.Engineering the phosphoinositide-binding profile of a class I pleckstrin homology domain.Classification of protein sequences by homology modeling and quantitative analysis of electrostatic similarity.
P2860
Q22010673-9EBC6CFB-0DE5-40C3-9296-C79DD90F04A3Q24292431-0FB6DCD3-A18B-4383-A30D-820A39CC2618Q24532099-91C61649-864F-4D48-86CA-CDD9C45AE6CDQ24554529-F7AB937D-90C0-4D6E-9289-EE417819EA83Q27628766-28C75768-69F8-4011-81B6-A7859E24A149Q27659565-5F1D6B55-2B03-48E9-B546-A22703EF9A0CQ27748825-B4B0D6F1-67DC-4BBA-9C15-51DFD9C90F84Q27766337-B92FAA7C-24C4-4989-A675-64B2FBC247F1Q28506616-02941F3B-CC42-4E88-80C6-1F365FD1315EQ28592987-F87202AB-99B9-4910-A593-FF52599862CBQ33665566-330C530A-8795-4F5A-81F7-195EB64340A1Q33896745-42684C11-115D-417E-AEF5-793209F840D5Q34116670-86CC33F0-151B-4725-9B8B-CBB2FED1ED3AQ34388235-543D272A-6BC4-4BB8-8EBE-B11DFF971EA9Q34575915-BC4EBF33-2F1F-4F36-A369-3FA9755C78A6Q35056507-E41D3D4B-9BEB-4B6E-8140-8011CBF2BE86Q36737651-6010BDFC-96EB-4E75-94C6-C12B993F2C78Q37903698-A7CFCD62-4B8D-4CC5-B8BF-BE2755F9EA79Q37970875-EFB02884-515F-4A60-9056-61CB8CD632FBQ38136655-C3C844C5-34E5-4C8E-A9AE-6ADA61570764Q38893703-12C308C5-246B-4589-8F13-61B0C75A986BQ40039722-3C6ECA8C-02D8-46C8-946E-BC9763BCA15FQ41080155-8059AE0E-65DC-4BE0-BF86-AD21995EA145Q41764505-3600AEDD-1440-40C5-9D02-67BD0073F02FQ42804184-4A988A26-B816-467F-BE18-6FE3F94D2ADAQ42830597-7A502C82-DE31-497B-A6A1-7A2D396D8AC1Q51843111-7A46793F-A88C-4757-B991-BD237C03969DQ52133653-66C71F16-36BE-4F56-8065-87A7C5879EDC
P2860
The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
The solution structure of the ...... nd pleckstrin homology domains
@ast
The solution structure of the ...... nd pleckstrin homology domains
@en
The solution structure of the ...... nd pleckstrin homology domains
@nl
type
label
The solution structure of the ...... nd pleckstrin homology domains
@ast
The solution structure of the ...... nd pleckstrin homology domains
@en
The solution structure of the ...... nd pleckstrin homology domains
@nl
prefLabel
The solution structure of the ...... nd pleckstrin homology domains
@ast
The solution structure of the ...... nd pleckstrin homology domains
@en
The solution structure of the ...... nd pleckstrin homology domains
@nl
P2093
P2860
P356
P1476
The solution structure of the ...... nd pleckstrin homology domains
@en
P2093
D Bar-Sagi
S Corblan-Garcia
S M Cahill
P2860
P304
P356
10.1074/JBC.272.48.30340
P407
P577
1997-11-28T00:00:00Z