MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway
about
Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitroMip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation.Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cellsKnockout of ERK5 causes multiple defects in placental and embryonic developmentTargeting MAPK Signaling in Age-Related Macular DegenerationMEK5/ERK5 pathway: the first fifteen yearsERK5 Mediated Signalling in Diabetic RetinopathyInteraction codes within the family of mammalian Phox and Bem1p domain-containing proteinsDifferential role of MEK5alpha and MEK5beta in BMK1/ERK5 activationWNK1 activates ERK5 by an MEKK2/3-dependent mechanismWNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertensionTargeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathwayERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expressionCalcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).MEK and the inhibitors: from bench to bedside.Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells.Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signalsModulation of protein kinase signaling cascades by palytoxin.MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via SrcReduced MCMV Δm157 viral clearance in the absence of TSAd.MAPK pathways in radiation responses.Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase signaling cascades.Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2.Wiring diagrams of MAPK regulation by MEKK1, 2, and 3.A transcription function for the T cell-specific adapter (TSAd) protein in T cells: critical role of the TSAd Src homology 2 domain.Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient miceMAPK signalling: ERK5 versus ERK1/2.G protein regulation of MAPK networks.Role of mitogen-activated protein kinase kinase kinases in signal integration.Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxinResveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade.Involvement of mixed lineage kinase 3 in cancer.The role of ERK5 in endothelial cell function.Stat3 upregulates MEK5 expression in human breast cancer cells.Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.Oncogenic signaling of MEK5-ERK5.An alternative mode of CD43 signal transduction activates pro-survival pathways of T lymphocytes.
P2860
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P2860
MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@ast
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@en
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@nl
type
label
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@ast
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@en
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@nl
prefLabel
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@ast
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@en
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@nl
P2093
P2860
P3181
P356
P1476
MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway
@en
P2093
B C Schaefer
E W Gelfand
G L Johnson
N L Johnson
T P Garrington
P2860
P304
P3181
P356
10.1074/JBC.M003719200
P407
P577
2001-02-16T00:00:00Z