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Similar effects of all WNK3 variants on SLC12 cotransportersActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesSerum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family membersMutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type IIWNK kinases, renal ion transport and hypertensionWNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cellsNeurotrophin-regulated signalling pathwaysWNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertensionDominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoformThe epidermal growth factor receptor critically regulates endometrial function during early pregnancy.LINGO-1 interacts with WNK1 to regulate nogo-induced inhibition of neurite extensionCalcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransportG alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).Effect of renal lipid accumulation on proximal tubule Na+/H+ exchange and ammonium secretion.WNK1 activates SGK1 to regulate the epithelial sodium channel.Kinase mutations in human disease: interpreting genotype-phenotype relationships.Zebrafish WNK lysine deficient protein kinase 1 (wnk1) affects angiogenesis associated with VEGF signaling.A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms.Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.WNK kinases influence TRPV4 channel function and localization.The WNKs: atypical protein kinases with pleiotropic actions.C. elegans STK39/SPAK ortholog-mediated inhibition of ClC anion channel activity is regulated by WNK-independent ERK kinase signalingTargeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signallingThe role of specific mitogen-activated protein kinase signaling cascades in the regulation of steroidogenesisc-KIT signaling is targeted by pathogenic Yersinia to suppress the host immune response.Exome sequencing identifies a novel gene, WNK1, for susceptibility to pelvic organ prolapse (POP).WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism.Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay.WNK1 activates large-conductance Ca2+-activated K+ channels through modulation of ERK1/2 signaling.WNK1 promotes PIP₂ synthesis to coordinate growth factor and GPCR-Gq signalingEndothelial protective genes induced by statin are mimicked by ERK5 activation as triggered by a drug combination of FTI-277 and GGTI-298.Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts.The dynamic stress-induced "O-GlcNAc-ome" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways.WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway.Identification of Differentially Expressed Genes through Integrated Study of Alzheimer's Disease Affected Brain RegionsRole of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension.Role of the WNK-activated SPAK kinase in regulating blood pressure.Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@ast
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@en
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@nl
type
label
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@ast
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@en
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@nl
prefLabel
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@ast
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@en
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@nl
P2093
P2860
P3181
P356
P1476
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism
@en
P2093
Byung-Hoon Lee
Lisa Lenertz
Melanie H Cobb
Steve Stippec
Youn-Kyoung Lee
P2860
P304
P3181
P356
10.1074/JBC.M313465200
P407
P577
2004-02-27T00:00:00Z