Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export
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p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumorsAnalysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expressionRole of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisNovel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functionsEpstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressorStructural Basis of Targeting the Exportin CRM1 in CancerNuclear export of proteins and drug resistance in cancerRegulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cellsCalpain activation is required for glutamate-induced p27 down-regulation in cultured cortical neuronsUSP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation.PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Profilin-1 overexpression inhibits proliferation of MDA-MB-231 breast cancer cells partly through p27kip1 upregulation.Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiationCharacterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppressionInducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase.Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agentsPhosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cellsEstrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosomeBCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein.Hunk is required for HER2/neu-induced mammary tumorigenesis.PI 3-kinase/Rac1 and ERK1/2 regulate FGF-2-mediated cell proliferation through phosphorylation of p27 at Ser10 by KIS and at Thr187 by Cdc25A/Cdk2p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer.Genotoxic stress and cellular stress alter the subcellular distribution of human T-cell leukemia virus type 1 tax through a CRM1-dependent mechanismAkt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical regionBlockade of protein geranylgeranylation inhibits Cdk2-dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy.p27Kip1 inhibition of GRB2-SOS formation can regulate Ras activation.Regulation of CDK4Intrinsically disordered proteins (IDPs) in trypanosomatids.Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial.
P2860
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P2860
Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@ast
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@en
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@nl
type
label
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@ast
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@en
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@nl
prefLabel
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@ast
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@en
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@nl
P2093
P356
P1476
Phosphorylation of p27Kip1 on ...... ing to CRM1 and nuclear export
@en
P2093
Keiichi I Nakayama
Keiko Nakayama
Noriko Ishida
Taichi Hara
Takumi Kamura
P304
P356
10.1074/JBC.C100762200
P407
P577
2002-04-26T00:00:00Z