Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner. - Wikidata - thesis-toulmin - TriplyDB

Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.

Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.

http://www.wikidata.org/entity/Q34206051

about

Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function Roles of mTOR Signaling in Brain Development Eliminating barriers to personalized medicine: learning from neurofibromatosis type 1 Pathological and molecular advances in pediatric low-grade astrocytoma Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2-dependent manner.Abnormal circadian oscillation of hippocampal MAPK activity and power spectrums in NF1 mutant mice.Using the neurofibromatosis tumor predisposition syndromes to understand normal nervous system development.Sex Is a major determinant of neuronal dysfunction in neurofibromatosis type 1.Neurofibromatosis type 1: modeling CNS dysfunction.Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development.Conditional astroglial Rictor overexpression induces malignant glioma in mice Loss of NF1 expression in human endothelial cells promotes autonomous proliferation and altered vascular morphogenesis.Skeletal muscle and motor deficits in Neurofibromatosis Type 1.The NF-κB RelB protein is an oncogenic driver of mesenchymal glioma Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1.Comparative characterization of the human and mouse third ventricle germinal zones Report from the fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop.Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner.Deconvoluting mTOR biology Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways Resting state functional MRI reveals abnormal network connectivity in neurofibromatosis 1.Targeted Therapy for MAPK Alterations in Pediatric Gliomas.Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner.Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma.A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies Optic pathway gliomas in neurofibromatosis-1: controversies and recommendations.Pediatric gliomas as neurodevelopmental disorders Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner.Pathogenesis of plexiform neurofibroma: tumor-stromal/hematopoietic interactions in tumor progression.NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1.Neuronal autophagy and neurodevelopmental disorders.Conditional KIAA1549:BRAF mice reveal brain region- and cell type-specific effects.ABCG1 maintains high-grade glioma survival in vitro and in vivo.Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target The ecology of brain tumors: lessons learned from neurofibromatosis-1.Review: low-grade gliomas as neurodevelopmental disorders: insights from mouse models of neurofibromatosis-1.The molecular and cell biology of pediatric low-grade gliomas.

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Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner.

http://www.wikidata.org/entity/Q34206051

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Neurofibromatosis-1 regulates ...... brain region-specific manner.

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Neurofibromatosis-1 regulates ...... brain region-specific manner.

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Neurofibromatosis-1 regulates ...... brain region-specific manner.

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Neurofibromatosis-1 regulates ...... brain region-specific manner.

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Neurofibromatosis-1 regulates ...... brain region-specific manner.

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Genes & Development

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Neurofibromatosis-1 regulates ...... a brain region-specific manner

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P2093

Crystal R White

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Da Yong Lee

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Ryan J Emnett

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Tu-Hsueh Yeh

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P2860

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

Defining the role of mTOR in cancer

The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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2317-2329

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scholarly article

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10.1101/GAD.1957110

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20

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24

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David H Gutmann

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2010-09-28T00:00:00Z

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46578870

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20876733

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2956210

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