Evidence for a common mechanism of SIRT1 regulation by allosteric activators - Wikidata - thesis-toulmin - TriplyDB

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

http://www.wikidata.org/entity/Q28286859

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AROS has a context-dependent effect on SIRT1 Epigenetics and aging SIRT1 and Kidney Function Sirtuin functions and modulation: from chemistry to the clinic Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Resveratrol Inhibition of Cellular Respiration: New Paradigm for an Old Mechanism Interdependence of nutrient metabolism and the circadian clock system: Importance for metabolic health Potential Modulation of Sirtuins by Oxidative Stress Sirt1 and the Mitochondria Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases Resveratrol: A Focus on Several Neurodegenerative Diseases Sirtuins in epigenetic regulation Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation.Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation.Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophy Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism The role of sirtuins in cardiac disease Nutraceuticals and Their Potential to Treat Duchenne Muscular Dystrophy: Separating the Credible from the Conjecture Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds Metabolism in HD: still a relevant mechanism?Nuclear DNA damage signalling to mitochondria in ageing Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile Resveratrol Enhances Neuroplastic Changes, Including Hippocampal Neurogenesis, and Memory in Balb/C Mice at Six Months of Age Synthesis and Assay of SIRT1-Activating Compounds Research Advances on Hepatotoxicity of Herbal Medicines in China A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions.Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease.Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.Berry phenolics of grapevine under challenging environments.Methylomic Aging as a Window onto the Influence of Lifestyle: Tobacco and Alcohol Use Alter the Rate of Biological Aging.Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation.Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet Small-molecule allosteric activators of sirtuins.Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK.FoxO3 increases miR-34a to cause palmitate-induced cholangiocyte lipoapoptosis.Recent progress in metabolic signaling pathways regulating aging and life span The anti-aging effects of Ludwigia octovalvis on Drosophila melanogaster and SAMP8 mice The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease Sirtuins: guardians of mammalian healthspan.

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P2860

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

http://www.wikidata.org/entity/Q28286859

description

2013 nî lūn-bûn

@nan

2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

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type

label

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

@nl

prefLabel

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

@ast

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

@en

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

@nl

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Evidence for a common mechanism of SIRT1 regulation by allosteric activators

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Alvin J Y Ling

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Ana P Gomes

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April W Case

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Charles A Blum

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Eli R Schuman

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George P Vlasuk

http://www.w3.org/2001/XMLSchema#string

Han Dai

http://www.w3.org/2001/XMLSchema#string

Huizhen Zhao

http://www.w3.org/2001/XMLSchema#string

James L Ellis

http://www.w3.org/2001/XMLSchema#string

Jeremy S Disch

http://www.w3.org/2001/XMLSchema#string

P2860

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation

SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator

SRT1720 improves survival and healthspan of obese mice

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

CBP/p300-mediated acetylation of histone H3 on lysine 56

From sirtuin biology to human diseases: an update

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Anabela Pinto Rolo

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