Exon/intron organization, chromosome localization, alternative splicing, and transcription units of the human apolipoprotein E receptor 2 gene
about
Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissueNormal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1A secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signalingA third major locus for autosomal dominant hypercholesterolemia maps to 1p34.1-p32Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cellsExpression in vitro of alternatively spliced variants of the messenger RNA for human apolipoprotein E receptor-2 identified in human tissues by ribonuclease protection assaysThe transmembrane domain and PXXP motifs of ApoE receptor 2 exclude it from carrying out clathrin-mediated endocytosisApolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cellsDifferential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis ratesThe reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2The low density lipoprotein receptor gene family. Differential expression of two alpha2-macroglobulin receptors in the brainAlternative splicing in the ligand binding domain of mouse ApoE receptor-2 produces receptor variants binding reelin but not alpha 2-macroglobulinDifferential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learningDeletion of selenoprotein P results in impaired function of parvalbumin interneurons and alterations in fear learning and sensorimotor gatingGene expression profiling of differentially expressed genes in granulosa cells of bovine dominant follicles using suppression subtractive hybridization.A statistical method for predicting splice variants between two groups of samples using GeneChip expression array dataPolymorphism in maternal LRP8 gene is associated with fetal growthApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in MiceFood-entrained rhythmic expression of apolipoprotein E expression in the hypothalamus of rats.Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase.Clusterin is a ligand for apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR) and signals via the Reelin-signaling pathway.A minimal binding domain of the low density lipoprotein receptor family.Functional Roles of the Interaction of APP and Lipoprotein Receptors.Interaction of beta2-glycoprotein I with members of the low density lipoprotein receptor family.Structural basis for ligand capture and release by the endocytic receptor ApoER2.Very-low-density lipoprotein binding to the apolipoprotein E receptor 2 is enhanced by lipoprotein lipase, and does not require apolipoprotein E.Lipophorin receptor of Bombyx mori: cDNA cloning, genomic structure, alternative splicing, and isolation of a new isoform.Organization and developmental expression of the mosquito vitellogenin receptor gene.Molecular cloning, expression and association study with reproductive traits of the duck LRP8 gene.How multi-scale structural biology elucidated context-dependent variability in ectodomain conformation along with the ligand capture and release cycle for LDLR family members.Polymorphisms in the human apolipoprotein E receptor 2 gene in Japanese sporadic Alzheimer's disease patients.
P2860
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P2860
Exon/intron organization, chromosome localization, alternative splicing, and transcription units of the human apolipoprotein E receptor 2 gene
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@ast
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@en
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@nl
type
label
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@ast
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@en
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@nl
prefLabel
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@ast
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@en
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@nl
P2093
P2860
P356
P1476
Exon/intron organization, chro ...... olipoprotein E receptor 2 gene
@en
P2093
T T Yamamoto
P2860
P304
P356
10.1074/JBC.272.13.8498
P407
P577
1997-03-28T00:00:00Z