FINDSITE: a threading-based approach to ligand homology modeling
about
Modeling enzyme-ligand binding in drug discoveryThe use of evolutionary patterns in protein annotationThe Mycobacterium tuberculosis drugome and its polypharmacological implicationsA comprehensive survey of small-molecule binding pockets in proteinsAutomatic generation of bioinformatics tools for predicting protein-ligand binding sitesHOMCOS: an updated server to search and model complex 3D structuresProtein ligand-specific binding residue predictions by an ensemble classifierProBiS-ligands: a web server for prediction of ligands by examination of protein binding sites.Computational analysis of membrane proteins: the largest class of drug targets.Q-Dock(LHM): Low-resolution refinement for ligand comparative modeling.The utility of geometrical and chemical restraint information extracted from predicted ligand-binding sites in protein structure refinementComprehensive structural and functional characterization of the human kinome by protein structure modeling and ligand virtual screening.Discovery of Mycobacterium tuberculosis InhA Inhibitors by Binding Sites Comparison and Ligands Prediction.How noise in force fields can affect the structural refinement of protein models?Elastic network normal modes provide a basis for protein structure refinementPrediction and experimental validation of enzyme substrate specificity in protein structures.Betaalpha-hairpin clamps brace betaalphabeta modules and can make substantive contributions to the stability of TIM barrel proteins.Experimental validation of FINDSITE(comb) virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders.GalaxySite: ligand-binding-site prediction by using molecular docking.HemeBIND: a novel method for heme binding residue prediction by combining structural and sequence informationKnowledge-based annotation of small molecule binding sites in proteins.BSP-SLIM: a blind low-resolution ligand-protein docking approach using predicted protein structuresCross-reactivity virtual profiling of the human kinome by X-react(KIN): a chemical systems biology approachIdentification of ligand templates using local structure alignment for structure-based drug design.FINDSITE(comb): a threading/structure-based, proteomic-scale virtual ligand screening approachStructure-based systems biology for analyzing off-target bindingLarge-scale binding ligand prediction by improved patch-based method Patch-Surfer2.0.Comprehensive prediction of drug-protein interactions and side effects for the human proteome.PatchSurfers: Two methods for local molecular property-based binding ligand predictionBioLiP: a semi-manually curated database for biologically relevant ligand-protein interactionsAPoc: large-scale identification of similar protein pockets.Are predicted protein structures of any value for binding site prediction and virtual ligand screening?Systems-level understanding of ethanol-induced stresses and adaptation in E. coli.Beyond structural genomics: computational approaches for the identification of ligand binding sites in protein structures.Computational analyses of the catalytic and heparin-binding sites and their interactions with glycosaminoglycans in glycoside hydrolase family 79 endo-β-D-glucuronidase (heparanase).eFindSite: Enhanced Fingerprint-Based Virtual Screening Against Predicted Ligand Binding Sites in Protein Models.GeauxDock: A novel approach for mixed-resolution ligand docking using a descriptor-based force field.Assessing the similarity of ligand binding conformations with the Contact Mode Score.Considerations of Protein Subpockets in Fragment-Based Drug Design.TargetATPsite: a template-free method for ATP-binding sites prediction with residue evolution image sparse representation and classifier ensemble.
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P2860
FINDSITE: a threading-based approach to ligand homology modeling
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
FINDSITE: a threading-based approach to ligand homology modeling
@ast
FINDSITE: a threading-based approach to ligand homology modeling
@en
FINDSITE: a threading-based approach to ligand homology modeling
@nl
type
label
FINDSITE: a threading-based approach to ligand homology modeling
@ast
FINDSITE: a threading-based approach to ligand homology modeling
@en
FINDSITE: a threading-based approach to ligand homology modeling
@nl
prefLabel
FINDSITE: a threading-based approach to ligand homology modeling
@ast
FINDSITE: a threading-based approach to ligand homology modeling
@en
FINDSITE: a threading-based approach to ligand homology modeling
@nl
P2860
P1476
FINDSITE: a threading-based approach to ligand homology modeling
@en
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000405
P407
P577
2009-06-01T00:00:00Z