Focal adhesion kinase and protein kinase B cooperate to suppress doxorubicin-induced apoptosis of breast tumor cells
about
A novel association between p130Cas and resistance to the chemotherapeutic drug adriamycin in human breast cancer cells.FAK and paxillin, two potential targets in pancreatic cancerIntrinsic chemoresistance to gemcitabine is associated with constitutive and laminin-induced phosphorylation of FAK in pancreatic cancer cell lines.Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer.Fever-range whole body thermotherapy combined with oxaliplatin: a curative regimen in a pre-clinical breast cancer modelFocal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).Fenretinide Perturbs Focal Adhesion Kinase in Premalignant and Malignant Human Oral Keratinocytes. Fenretinide's Chemopreventive Mechanisms Include ECM Interactions.A systems biology approach for pathway level analysis.Changes in focal adhesion kinase expression in rats with collagen-induced arthritis and efficacy of intervention with disease modifying anti-rheumatic drugs alone or in combinationProlactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity.Focal adhesion kinase: a promising target for anticancer therapy.Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo.Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression.Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer.The dual kinase complex FAK-Src as a promising therapeutic target in cancerInfluence of stress on extracellular matrix and integrin biology.p53 regulates cytoskeleton remodeling to suppress tumor progression.The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer
P2860
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P2860
Focal adhesion kinase and protein kinase B cooperate to suppress doxorubicin-induced apoptosis of breast tumor cells
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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scientific journal article
@en
vedecký článok (publikovaný 2006/10/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/01)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في أكتوبر 2006)
@ar
name
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@ast
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@en
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@nl
type
label
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@ast
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@en
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@nl
prefLabel
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@ast
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@en
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@nl
P2093
P356
P1476
Focal adhesion kinase and prot ...... poptosis of breast tumor cells
@en
P2093
Annamarie Camier
Bob van de Water
Ine B. Tijdens
Maroesja J. van Nimwegen
Merei Huigsloot
P304
P356
10.1124/MOL.106.026195
P577
2006-10-01T00:00:00Z