GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion.
about
Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testesIn vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinaseA mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding proteinIdentification of Aurora kinases as RasGAP Src homology 3 domain-binding proteinsThe Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, HckRas GTPase-activating protein binds to Akt and is required for its activationTwo regions with differential growth-modulating activity in the N-terminal domain of ras GTPase-activating protein (p120GAP) src homology and Gly-Ala-Pro-rich regionsA novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regionsStimulation of gene induction and cell growth by the Ras effector RlfRas-GTPase activating protein inhibition specifically induces apoptosis of tumour cells.Ras-GAP controls Rho-mediated cytoskeletal reorganization through its SH3 domain.The Ras-GTPase-activating protein SH3 domain is required for Cdc2 activation and mos induction by oncogenic Ras in Xenopus oocytes independently of mitogen-activated protein kinase activation.Muscarinic receptors transform NIH 3T3 cells through a Ras-dependent signalling pathway inhibited by the Ras-GTPase-activating protein SH3 domain.Direct spatial control of Epac1 by cyclic AMP.Human IL-12 p40 as a reporter gene for high-throughput screening of engineered mouse embryonic stem cellsRetrotransposition and mutation events yield Rap1 GTPases with differential signalling capacityA Ras-dependent pathway regulates RNA polymerase II phosphorylation in cardiac myocytes: implications for cardiac hypertrophy.Signaling from Ras to Rac and beyond: not just a matter of GEFs.Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP.Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.The small GTPase Rap1 is required for Mn(2+)- and antibody-induced LFA-1- and VLA-4-mediated cell adhesion.The small GTPase Rap1 is activated by turbulence and is involved in integrin [alpha]IIb[beta]3-mediated cell adhesion in human megakaryocytes.Regulation of the Ras signalling network.AF6 negatively regulates Rap1-induced cell adhesion.Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinaseThe ras signaling pathway mimics insulin action on glucose transporter translocationDifferential antagonism of Ras biological activity by catalytic and Src homology domains of Ras GTPase activation protein.The small GTPase, Rap1, mediates CD31-induced integrin adhesion.Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth.The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway.Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.Association and phosphorylation-dependent dissociation of proteins in the insulin receptor complexFunctional role of GTPase-activating protein in cell transformation by pp60v-srcNonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours.The src homology 2 and phosphotyrosine binding domains of the ShcC adaptor protein function as inhibitors of mitogenic signaling by the epidermal growth factor receptor.Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase.Ethanol inhibits insulin receptor substrate-1 tyrosine phosphorylation and insulin-stimulated neuronal thread protein gene expression.p120 GAP requirement in normal and malignant human hematopoiesis.Involvement of a phosphotyrosine protein phosphatase in the suppression of platelet-derived growth factor receptor autophosphorylation in ras-transformed cells.
P2860
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P2860
GTPase-activating protein SH2-SH3 domains induce gene expression in a Ras-dependent fashion.
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@ast
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@en
type
label
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@ast
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@en
prefLabel
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@ast
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@en
P2093
P2860
P356
P1476
GTPase-activating protein SH2- ...... on in a Ras-dependent fashion.
@en
P2093
P2860
P304
P356
10.1128/MCB.12.8.3425
P407
P577
1992-08-01T00:00:00Z