Fluorescence spectroscopic profiling of compound libraries. - Wikidata - thesis-toulmin - TriplyDB

Fluorescence spectroscopic profiling of compound libraries.

Fluorescence spectroscopic profiling of compound libraries.

http://www.wikidata.org/entity/Q33325308

about

High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships Development and utility of an in vitro, fluorescence-based assay for the discovery of novel compounds against dengue 2 viral protease Applications of Replicating-Competent Reporter-Expressing Viruses in Diagnostic and Molecular Virology Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?Physicochemical characterization of a thermostable alcohol dehydrogenase from Pyrobaculum aerophilum Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors Rational methods for the selection of diverse screening compounds Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1 Novel patient cell-based HTS assay for identification of small molecules for a lysosomal storage disease A dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosis Perspectives on validation of high-throughput assays supporting 21st century toxicity testing Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site Modeling error in experimental assays using the bootstrap principle: understanding discrepancies between assays using different dispensing technologies.Docking Screens for Novel Ligands Conferring New Biology.Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease High-throughput identification of promiscuous inhibitors from screening libraries with the use of a thiol-containing fluorescent probe A Quantitative High-Throughput Screening Data Analysis Pipeline for Activity Profiling.A high throughput fluorescence polarization assay for inhibitors of the GoLoco motif/G-alpha interaction.A specific mechanism for nonspecific activation in reporter-gene assays A robotic platform for quantitative high-throughput screening Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay Characterization and optimization of a red-shifted fluorescence polarization ADP detection assay.Advances in improving the quality and flexibility of compound management.A dual-fluorescence high-throughput cell line system for probing multidrug resistance.A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries The pilot phase of the NIH Chemical Genomics Center.The identification, characterization and optimization of small molecule probes of cysteine proteases: experiences of the Penn Center for Molecular Discovery with cathepsin B and cathepsin L.A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase.Apparent activity in high-throughput screening: origins of compound-dependent assay interference A high-throughput screening compatible assay for activators and inhibitors of methionine sulfoxide reductase A A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics Identifying actives from HTS data sets: practical approaches for the selection of an appropriate HTS data-processing method and quality control review.A fluorescent, reagentless biosensor for ADP based on tetramethylrhodamine-labeled ParM.A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2 Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.Exploratory analysis of kinetic solubility measurements of a small molecule library Composition and applications of focus libraries to phenotypic assays Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biology

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P2860

Fluorescence spectroscopic profiling of compound libraries.

http://www.wikidata.org/entity/Q33325308

description

2008 nî lūn-bûn

@nan

2008 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի մարտին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Fluorescence spectroscopic profiling of compound libraries.

@ast

Fluorescence spectroscopic profiling of compound libraries.

@en

Fluorescence spectroscopic profiling of compound libraries.

@nl

type

label

Fluorescence spectroscopic profiling of compound libraries.

@ast

Fluorescence spectroscopic profiling of compound libraries.

@en

Fluorescence spectroscopic profiling of compound libraries.

@nl

prefLabel

Fluorescence spectroscopic profiling of compound libraries.

@ast

Fluorescence spectroscopic profiling of compound libraries.

@en

Fluorescence spectroscopic profiling of compound libraries.

@nl

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P1433

Journal of Medicinal Chemistry

P1476

Fluorescence spectroscopic profiling of compound libraries.

@en

P2093

Craig J Thomas

http://www.w3.org/2001/XMLSchema#string

Douglas S Auld

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James Inglese

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Jeremy Smith

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Paul Shinn

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Ruili Huang

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Yuhong Wang

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2363-2371

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scholarly article

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10.1021/JM701301M

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8

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51

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Christopher P Austin

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2008-03-26T00:00:00Z

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5489723

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18363325

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