Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression
about
Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionThe Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous ProteinsThe Role of the DNA Damage Response throughout the Papillomavirus Life CycleBrd4 activates P-TEFb for RNA polymerase II CTD phosphorylationBET domain co-regulators in obesity, inflammation and cancerAnalysis of the papillomavirus E2 and bromodomain protein Brd4 interaction using bimolecular fluorescence complementationInteraction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral ReplicationPapillomavirus E6 oncoproteins.Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway.Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis.An interactive web-based application for Comprehensive Analysis of RNAi-screen DataPapillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.NCoR1 mediates papillomavirus E8;E2C transcriptional repressionProliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatin.The cellular bromodomain protein Brd4 has multiple functions in E2-mediated papillomavirus transcription activationSystematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infectionsLarge scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions.Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.Use of epigenetic drugs in disease: an overview.Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3BEpigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.PubChem BioAssay: 2014 updateBrd4 is displaced from HPV replication factories as they expand and amplify viral DNAGenome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat.The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection.Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinomaIdentification and analysis of papillomavirus E2 protein binding sites in the human genome.Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.An interaction between human papillomavirus 16 E2 and TopBP1 is required for optimum viral DNA replication and episomal genome establishmentCell-based genomic screening: elucidating virus-host interactionsRNA interference for the treatment of papillomavirus disease.Virology and molecular pathogenesis of HPV (human papillomavirus)-associated oropharyngeal squamous cell carcinomaFailure to interact with Brd4 alters the ability of HPV16 E2 to regulate host genome expression and cellular movementCurrent understanding of the role of the Brd4 protein in the papillomavirus lifecycle.BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression.The papillomavirus E2 proteinsTandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral OncogenesHigh-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.
P2860
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P2860
Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression
description
2010 nî lūn-bûn
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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
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2010年论文
@wuu
name
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@ast
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@en
type
label
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@ast
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@en
prefLabel
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@ast
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@en
P2093
P2860
P356
P1476
Genome-wide siRNA screen ident ...... llomavirus oncogene expression
@en
P2093
Elizabeth A White
Jennifer A Smith
Maria L C Powell
Mathew E Sowa
Matthias Ottinger
P2860
P304
P356
10.1073/PNAS.0914818107
P407
P577
2010-02-02T00:00:00Z