Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.
about
Caught in the cross fire: p53 in inflammation.Effects of ploidy and recombination on evolution of robustness in a model of the segment polarity networkp53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening systemQuantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional AssayDivergent evolution of human p53 binding sites: cell cycle versus apoptosisA survey of genomic properties for the detection of regulatory polymorphisms.Noncanonical DNA motifs as transactivation targets by wild type and mutant p53Parallel analysis of tetramerization domain mutants of the human p53 protein using PCR colonies.Conservation of DNA-binding specificity and oligomerisation properties within the p53 family.Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.Single-nucleotide polymorphisms in the p53 signaling pathway.The Toll-like receptor gene family is integrated into human DNA damage and p53 networks.A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional networkHuman single-nucleotide polymorphisms alter p53 sequence-specific binding at gene regulatory elements.Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk.The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes.Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of DrosophilaInteractions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.Identification of new p53 target microRNAs by bioinformatics and functional analysisThe Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosisMicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanomaThe Environmental Polymorphism Registry: a unique resource that facilitates translational research of environmental diseaseWhole-genome cartography of p53 response elements ranked on transactivation potential.A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.Functional analyses of human DNA repair proteins important for aging and genomic stability using yeast geneticsDistinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.Transcriptional functionality of germ line p53 mutants influences cancer phenotype.Functional evolution of the p53 regulatory network through its target response elements.Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson.Versatile functions of p53 protein in multicellular organismsProbing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extractsRedefining the p53 response element.Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment.A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damage.p53 polymorphisms: cancer implications.Locus-specific databases in cancer: what future in a post-genomic era? The TP53 LSDB paradigm.An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation.Genetic Modifiers of the p53 Pathway.Human transcription factors in yeast: the fruitful examples of P53 and NF-кB.Functional analysis of CDKN2A/p16INK4a 5'-UTR variants predisposing to melanoma.
P2860
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P2860
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Functionally distinct polymorp ...... rgets for p53 transactivation.
@ast
Functionally distinct polymorp ...... rgets for p53 transactivation.
@en
type
label
Functionally distinct polymorp ...... rgets for p53 transactivation.
@ast
Functionally distinct polymorp ...... rgets for p53 transactivation.
@en
prefLabel
Functionally distinct polymorp ...... rgets for p53 transactivation.
@ast
Functionally distinct polymorp ...... rgets for p53 transactivation.
@en
P2093
P2860
P356
P1476
Functionally distinct polymorp ...... argets for p53 transactivation
@en
P2093
Alberto Inga
Daniel J Tomso
Daniel Menendez
Douglas A Bell
Francesca Storici
Gary S Pittman
Michelle R Campbell
P2860
P304
P356
10.1073/PNAS.0501721102
P407
P577
2005-04-20T00:00:00Z