Connexin43 mediates direct intercellular communication in human osteoblastic cell networks
about
Life cycle of connexins in health and diseaseConnexin 43 (GJA1) mutations cause the pleiotropic phenotype of oculodentodigital dysplasiaConnexin43 gap junctions in normal, regenerating, and cultured mouse bone marrow and in human leukemias: their possible involvement in blood formationConnexin-mimetic peptide Gap 27 decreases osteoclastic activityBone morphogenetic protein-2 (BMP-2) and transforming growth factor-beta1 (TGF-beta1) alter connexin 43 phosphorylation in MC3T3-E1 CellsConnexin 43 hemichannels and intracellular signaling in bone cellsDefining a minimal motif required to prevent connexin oligomerization in the endoplasmic reticulumConnexin46 is retained as monomers in a trans-Golgi compartment of osteoblastic cellsAge-related changes in gap junctional intercellular communication in osteoblastic cellsInhibition of gap junction intercellular communication by extremely low-frequency electromagnetic fields in osteoblast-like models is dependent on cell differentiation.Cell communication in a coculture system consisting of outgrowth endothelial cells and primary osteoblasts.Differentiation of human fetal osteoblastic cells and gap junctional intercellular communication.Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone.Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability.Syndromic and non-syndromic disease-linked Cx43 mutations.Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient miceGap junction intercellular communication: a review of a potential platform to modulate craniofacial tissue engineering.Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse modelGap junctional communication in osteocytes is amplified by low intensity vibrations in vitro.Up-regulation of BMP2/4 signaling increases both osteoblast-specific marker expression and bone marrow adipogenesis in Gja1Jrt/+ stromal cell cultures.Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysisCx43 and mechanotransduction in bone.Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation.Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress.Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodelingConnexins and pannexins in the skeleton: gap junctions, hemichannels and moreCONNEXIN 43 AND BONE: NOT JUST A GAP JUNCTION PROTEIN.Role of connexins and pannexins during ontogeny, regeneration, and pathologies of boneGap junctions and hemichannels in signal transmission, function and development of boneDefective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain.Connexin43 deficiency causes delayed ossification, craniofacial abnormalities, and osteoblast dysfunction.Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43.Beyond gap junctions: Connexin43 and bone cell signalingCell-cell communication in the osteoblast/osteocyte lineage.Gap junctional communication modulates gene expression in osteoblastic cellsConnexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading.Matrix-dependent adhesion mediates network responses to physiological stimulation of the osteocyte cell process.Calcium signalling and calcium transport in bone disease.Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1).ERp29 restricts Connexin43 oligomerization in the endoplasmic reticulum.
P2860
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P2860
Connexin43 mediates direct intercellular communication in human osteoblastic cell networks
description
1993 nî lūn-bûn
@nan
1993 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Connexin43 mediates direct int ...... man osteoblastic cell networks
@ast
Connexin43 mediates direct int ...... man osteoblastic cell networks
@en
type
label
Connexin43 mediates direct int ...... man osteoblastic cell networks
@ast
Connexin43 mediates direct int ...... man osteoblastic cell networks
@en
prefLabel
Connexin43 mediates direct int ...... man osteoblastic cell networks
@ast
Connexin43 mediates direct int ...... man osteoblastic cell networks
@en
P2093
P2860
P356
P1476
Connexin43 mediates direct int ...... man osteoblastic cell networks
@en
P2093
A J Robertson
P M Warlow
R Civitelli
T H Steinberg
P2860
P304
P356
10.1172/JCI116406
P407
P577
1993-05-01T00:00:00Z