Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways
about
The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathwayActivation of the RalGEF/Ral pathway promotes prostate cancer metastasis to boneBit1 in anoikis resistance and tumor metastasisPutative biomarkers and targets of estrogen receptor negative human breast cancerThe RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector InteractionThe Structure of the RLIP76 RhoGAP-Ral Binding Domain Dyad: Fixed Position of the Domains Leads to Dual Engagement of Small G Proteins at the MembraneHSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivoRLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosisInvolvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformationRal GTPases: crucial mediators of exocytosis and tumourigenesisRalB mobilizes the exocyst to drive cell migrationPhosphorylation of RalB is important for bladder cancer cell growth and metastasisRalA activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells.Differential gene expression in chemically induced mouse lung adenomas.Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma.Alteration in protein expression in estrogen receptor alpha-negative human breast cancer tissues indicates a malignant and metastatic phenotype.Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation.Human RAS superfamily proteins and related GTPases.Immunogenicity of Ra1A and its tissue-specific expression in hepatocellular carcinoma.Long noncoding RNA MRCCAT1 promotes metastasis of clear cell renal cell carcinoma via inhibiting NPR3 and activating p38-MAPK signalingMetastasis of tumor cells is enhanced by downregulation of Bit1.Mdr1 gene expression and mutations in Ras proto-oncogenes in acute myeloid leukemia.TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulationA Ral guanine exchange factor-Ral pathway is conserved in Drosophila melanogaster and sheds new light on the connectivity of the Ral, Ras, and Rap pathways5-Formylhonokiol exerts anti-angiogenesis activity via inactivating the ERK signaling pathway.Distinct requirements for Ras oncogenesis in human versus mouse cells.Imbalanced expression of mitogen-activated protein kinase phosphatase-1 and phosphorylated extracellular signal-regulated kinases in lung squamous cell carcinoma.The anti-inflammatory TIPE2 is an inhibitor of the oncogenic Ras.Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer.Overexpression of RalBP1 in colorectal cancer is an independent predictor of poor survival and early tumor relapseThe roles of MAPKs in disease.Molecular mechanism of hepatitis B virus (HBV) on suppression of raf kinase inhibitor protein (RKIP) expression.Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling.Osteosarcoma metastasis: prospective role of ezrin.The small G-protein RalA stimulates metastasis of transformed cells.A family affair: A Ral-exocyst-centered network links Ras, Rac, Rho signaling to control cell migration.Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansionProtein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.The phosphatidylinositol-3 kinase pathway regulates bladder cancer cell invasion.Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10.
P2860
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P2860
Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Signal pathways which promote ...... anine exchange factor pathways
@ast
Signal pathways which promote ...... anine exchange factor pathways
@en
type
label
Signal pathways which promote ...... anine exchange factor pathways
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Signal pathways which promote ...... anine exchange factor pathways
@en
prefLabel
Signal pathways which promote ...... anine exchange factor pathways
@ast
Signal pathways which promote ...... anine exchange factor pathways
@en
P2093
P2860
P1476
Signal pathways which promote ...... anine exchange factor pathways
@en
P2093
P2860
P304
P356
10.1128/MCB.21.17.5958-5969.2001
P407
P577
2001-09-01T00:00:00Z