Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.
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The gene therapy journey for hemophilia: are we there yet?Cardiovascular gene therapy for myocardial infarctionImmunology of AAV-Mediated Gene Transfer in the EyeGene therapy for hemophiliaViral-mediated Ntf3 overexpression disrupts innervation and hearing in nondeafened guinea pig cochleaeGene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockadeBroadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection.Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissueStrategies to circumvent humoral immunity to adeno-associated viral vectors.Robust Long-term Transduction of Common Marmoset Neuromuscular Tissue With rAAV1 and rAAV9.Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapyHumoral Immune Response to AAV.Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies.Anti-CD20 as the B-Cell Targeting Agent in a Combined Therapy to Modulate Anti-Factor VIII Immune Responses in Hemophilia a Inhibitor MicePre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors.New and improved AAVenues: current status of hemophilia B gene therapy.Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune TargetingSystemic delivery of adeno-associated viral vectors.High-Density Recombinant Adeno-Associated Viral Particles are Competent Vectors for In Vivo Transduction.Optimized AAV rh.10 Vectors That Partially Evade Neutralizing Antibodies during Hepatic Gene Transfer.rAAV9 combined with renal vein injection is optimal for kidney-targeted gene delivery: conclusion of a comparative study.Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.Prevalence of AAV1 neutralizing antibodies and consequences for a clinical trial of gene transfer for advanced heart failure.Overcoming preexisting humoral immunity to AAV using capsid decoysFeasibility and safety of systemic rAAV9-hNAGLU delivery for treating mucopolysaccharidosis IIIB: toxicology, biodistribution, and immunological assessments in primates.Safety of Intradiaphragmatic Delivery of Adeno-Associated Virus-Mediated Alpha-Glucosidase (rAAV1-CMV-hGAA) Gene Therapy in children affected by Pompe Disease.Emerging Issues in AAV-Mediated In Vivo Gene Therapy.Gene Therapy With Regulatory T Cells: A Beneficial Alliance.
P2860
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P2860
Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Pharmacological modulation of ...... ene transfer for hemophilia B.
@ast
Pharmacological modulation of ...... ene transfer for hemophilia B.
@en
type
label
Pharmacological modulation of ...... ene transfer for hemophilia B.
@ast
Pharmacological modulation of ...... ene transfer for hemophilia B.
@en
prefLabel
Pharmacological modulation of ...... ene transfer for hemophilia B.
@ast
Pharmacological modulation of ...... ene transfer for hemophilia B.
@en
P2093
P2860
P356
P1433
P1476
Pharmacological modulation of ...... gene transfer for hemophilia B
@en
P2093
Federico Mingozzi
J Fraser Wright
Mark E Metzger
Robert E Donahue
Samuel L Murphy
Sandra D Price
Shangzhen Zhou
Shyrie C Edmonson
Yifeng Chen
P2860
P304
P356
10.1038/MT.2012.84
P577
2012-05-08T00:00:00Z