ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
about
The DNA damage response pathway in normal hematopoiesis and malignancies.Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition.When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies.A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.
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ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 October 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
ATM/G6PD-driven redox metaboli ...... nce in acute myeloid leukemia.
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ATM/G6PD-driven redox metaboli ...... nce in acute myeloid leukemia.
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type
label
ATM/G6PD-driven redox metaboli ...... nce in acute myeloid leukemia.
@en
ATM/G6PD-driven redox metaboli ...... nce in acute myeloid leukemia.
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prefLabel
ATM/G6PD-driven redox metaboli ...... nce in acute myeloid leukemia.
@en
ATM/G6PD-driven redox metaboli ...... nce in acute myeloid leukemia.
@nl
P2093
P2860
P50
P356
P1476
ATM/G6PD-driven redox metaboli ...... ance in acute myeloid leukemia
@en
P2093
Amit Kumar
Andrii I Rozhok
Biniam Adane
Craig T Jordan
Daniel A Pollyea
Francesca Alvarez-Calderon
Kirk C Hansen
Michael F Wempe
Natalie J Serkova
P2860
P304
E6669-E6678
P356
10.1073/PNAS.1603876113
P407
P577
2016-10-10T00:00:00Z