about
ATM serine/threonine kinaseTransformation related protein 53Ataxia telangiectasia mutatedCyclin dependent kinase inhibitor 2AMembrane metallo endopeptidaseTelomerase reverse transcriptaseCheckpoint kinase 1CST telomere replication complex component 1Phospholipase A2 receptor 1Wnt family member 16Ataxia telangiectasia mutated (Includes complementation groups A, C and D), isoform CRA_aSerine-protein kinase ATMTumor suppressor ARFSerine/threonine-protein kinase ATRCTS telomere maintenance complex component 1Plasminogen activator inhibitor 1Phospholipase A2 receptor 1Wingless-type MMTV integration site family, member 16DNA polymerase epsilon noncatalytic subunit YBR278WDNA polymerase epsilon noncatalytic subunit YDR121WTumor protein p53Telomerase reverse transcriptaseSerpin family E member 1ATR serine/threonine kinaseCST telomere replication complex component 1Cyclin-dependent kinase inhibitor 1AWnt family member 16Serine (or cysteine) peptidase inhibitor, clade E, member 1Serpin family E member 1Membrane metalloendopeptidaseCyclin dependent kinase inhibitor 2ACyclin dependent kinase inhibitor 1AATR serine/threonine kinaseCheckpoint kinase 2Cyclin dependent kinase inhibitor 1ATelomerase reverse transcriptase
P682
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)Neprilysin is identical to skin fibroblast elastase: its role in skin aging and UV responsesDirect evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferationExtension of life-span by introduction of telomerase into normal human cellsPlasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescenceModulation of the Senescence-Associated Inflammatory Phenotype in Human Fibroblasts by Olive Phenols.The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.The relationship of mammal survivorship and body mass modeled by metabolic and vitality theories
P921
Q141591-6922E0FE-9F6D-4319-A98D-6881AB3011ECQ141591-C70491AC-1A5A-44AB-AA1D-3C8BB112785DQ14818136-0A6CD61D-70E6-4468-81CD-65AC0077D11AQ14818136-1D93C070-A889-4124-89F5-5D20056FEF5CQ14872812-0292D08A-5DD0-4170-8CF4-82EF1FBD600FQ14907028-96930737-CF82-4BF5-8A7A-D8FBD8510BB7Q14911852-C6DD197D-5D3D-46E7-A328-E58D3044BF81Q15315162-F122D05E-1B96-4A71-AA10-869290A8D6CEQ21109168-744AE7F1-7529-4AD6-A912-F6F4363954A8Q21111548-88BA6C50-7616-4DC1-8ECA-5BADED110A19Q21119732-0D53BEF8-EA61-4024-9FA4-BD8E1A984696Q21123981-10EB396A-E7D0-4379-959F-7FD7FAB9BF98Q21137179-87BB874F-C9E3-4F93-8EEB-ADCD0E429B1FQ21145406-7815F050-C09D-48E4-A10D-1CDAE4DFE04EQ21499012-A5992595-0C34-4228-991C-D71132DD58CAQ21499134-8B8D3804-3DE4-4BE0-924C-5E83EECC518DQ21499397-F4E2225D-579E-4F26-B9F1-D8489F50F43BQ21987826-65DC0175-9FF9-4B0D-9178-B3C00E6618D9Q21989376-1F9DBA67-4E58-4C3D-A4EE-E74881B466AEQ21992019-6EFEDF96-0539-42E7-96CC-84FD7A9A9E5FQ27547937-28621014-803B-4F03-846B-A9EB3A2C7930Q27551838-4D25ECCF-DB6B-4092-BC4D-1BBC6F06D61DQ283350-7DD47F1D-B7BA-4D10-A3E8-A2284C9B26E8Q28557323-2CAE0790-833C-4070-9CBC-C9385F93FEFFQ28561352-8BE307AD-5642-4DA9-8024-AB891C67A144Q29517362-C48ED77C-A804-4BB5-8338-017202EA1545Q29520867-0C63889D-9159-4BC9-94EA-897401C66D81Q29521673-E2EDEA6E-835B-48CE-A564-0845D6E62973Q29525673-EE1C6385-2798-42DB-8C80-9E8DC59C349EQ29530196-318BC8D1-2DF4-4FF3-842A-70242F70EC2BQ410485-84C9AC08-8BF1-4B34-B581-B6FE1E9CCD22Q414232-5EEE3C95-E6BD-4F6C-A1CA-DC0549426F05Q416259-5B1BC6A4-17A3-4739-9D79-BA20F0D788BAQ423686-25E50A60-081B-4DCF-9A3E-15913967290FQ4812911-E765F58E-B7C0-443C-B8AC-CDE283972889Q5011104-AC310E6F-B825-4239-860B-7AE22DBA6680Q55199880-78308F8D-1DD9-46CB-9927-6A34EB199E96Q7697809-131BC4F2-2683-4380-8CD7-77E9C26DADD5
P682
Q24293520-792FAAA1-754A-4DF8-8B38-0E7852D88DFBQ24301332-F088C863-EC41-42C7-9E0D-F3D431D56788Q24304496-3362D8EC-F929-460D-92EE-FA7C67B68661Q24336088-DE1450D9-2396-4A9E-BEE9-2274D2D49CE2Q34196515-1E1000C8-A12E-4419-8F39-3E4DA0EF8E48Q47165608-2C3B7B1A-7AE2-44E6-ADF4-A6BA9155E3B6Q55637473-97284B8C-0638-48B4-841B-19761FBA7612Q64329593-6D5C0F42-F3D9-4D0A-B914-3B1A67E2859D
P921
description
A cell aging process associate ...... rtening and/or cellular aging.
@en
biologisch proces
@nl
name
replicative senescence
@en
type
label
replicative senescence
@en
altLabel
GO:0090399
@en
prefLabel
replicative senescence
@en
P279
P2888
P686
GO:0090399