about
P688
Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesiclesA novel hook-related protein family and the characterization of hook-related protein 1Akt/PKB regulates actin organization and cell motility via Girdin/APEA Conserved Role for Girdin in Basal Body Positioning and CiliogenesisA G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/GirdinGIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling.GIV/Girdin activates Gαi and inhibits Gαs via the same motifTyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration.Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.
P921
Q24297434-F8315E38-64CE-44EE-B11F-1252FB5C2C88Q24301661-CEFA6CCA-2DFA-4FC8-A6BE-871D09F65DDCQ24319781-91256202-0C3C-44A9-BB43-57646221C020Q28114965-9F1C7C1E-7638-48BF-985E-F73291729AC1Q33948589-C3E84156-16B1-43FB-B316-4318CB2F9E77Q34504260-DD4DB868-43AE-4A41-9F80-EBFB0BBC5FC0Q36747496-985D5751-8518-489B-BDCA-418544BB6E27Q37117635-838FE349-780E-4297-AA2C-4CB36AD44F41Q37304977-835672D1-0F6D-4031-91CE-CDA1047ADE7FQ39466800-A800059E-54D0-4EE4-A864-B6D9A3F749B6Q51316906-847DA03A-8A4A-4FCA-A784-C02DA84ED60C
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in Coiled-coil domain containing 88A
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Coiled-coil domain containing 88A
@en
Coiled-coil domain containing 88A
@nl
type
label
Coiled-coil domain containing 88A
@en
Coiled-coil domain containing 88A
@nl
altLabel
AKT-phosphorylation enhancer
@en
APE
@en
Akt phosphorylation enhancer
@en
CCDC88A
@en
Coiled-coil domain-containing protein 88A
@en
GIV
@en
HkRP1
@en
Hook-related protein 1
@en
g alpha-interacting vesicle-associated protein
@en
girders of actin filament
@en
prefLabel
Coiled-coil domain containing 88A
@en
Coiled-coil domain containing 88A
@nl
P637
P680
P681
P682
P705
P352
P637
P31
P352
P637
NP_001129069
NP_001241872
NP_001352409
XP_005264475
XP_005264478
XP_005264483
XP_011531268
XP_011531269
XP_011531270
P680
P681
P682
P702
P703
P705
ENSP00000263630
ENSP00000338728
ENSP00000390012
ENSP00000404431
ENSP00000405080
ENSP00000410608
ENSP00000413401
ENSP00000415267
ENSP00000480931
ENSP00000493638