Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin. - Wikidata - wikimedia - TriplyDB

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.

http://www.wikidata.org/entity/Q34504260

about

Heterotrimeric G proteins as emerging targets for network based therapy in cancer: End of a long futile campaign striking heads of a Hydra Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors.Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins.CCDC88A mutations cause PEHO-like syndrome in humans and mouse Glycan Sulfation Modulates Dendritic Cell Biology and Tumor Growth.GIV/Girdin activates Gαi and inhibits Gαs via the same motif AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin.The untapped potential of tyrosine-based G protein signaling.Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.GIV/girdin binds exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles.Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif.Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin.Mitochondrial BMI1 maintains bioenergetic homeostasis in cells.Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein.Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling.Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple.A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteins

P2860

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P2860

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin.

http://www.wikidata.org/entity/Q34504260

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

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2014年论文

@wuu

name

Structural basis for activatio ...... ctor receptors via GIV/Girdin.

@ast

Structural basis for activatio ...... ctor receptors via GIV/Girdin.

@en

Structural basis for activatio ...... ctor receptors via GIV/Girdin.

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type

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Structural basis for activatio ...... ctor receptors via GIV/Girdin.

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Structural basis for activatio ...... ctor receptors via GIV/Girdin.

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Structural basis for activatio ...... ctor receptors via GIV/Girdin.

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prefLabel

Structural basis for activatio ...... ctor receptors via GIV/Girdin.

@ast

Structural basis for activatio ...... ctor receptors via GIV/Girdin.

@en

Structural basis for activatio ...... ctor receptors via GIV/Girdin.

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MBC.E14-05-0978

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Molecular Biology of the Cell

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Structural basis for activatio ...... ctor receptors via GIV/Girdin.

@en

P2093

Changsheng Lin

http://www.w3.org/2001/XMLSchema#string

Inmaculada Lopez-Sanchez

http://www.w3.org/2001/XMLSchema#string

Jason Ear

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Krishna Midde

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Mikel Garcia-Marcos

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Pradipta Ghosh

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Ruben Abagyan

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P2860

Intrinsically unstructured proteins and their functions

Function and structure of inherently disordered proteins

Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells

Akt/PKB regulates actin organization and cell motility via Girdin/APE

Shc phosphotyrosine-binding domain dominantly interacts with epidermal growth factor receptors and mediates Ras activation in intact cells

The RCSB Protein Data Bank: redesigned web site and web services

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases

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3654-3671

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10.1091/MBC.E14-05-0978

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22

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25

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2014-09-03T00:00:00Z

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vascular endothelial growth factor receptor 2 binding

Coiled-coil domain containing 88A

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4230624

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