Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
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A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implicationsFunctional mapping of protein kinase A reveals its importance in adult Schistosoma mansoni motor activityAnalyses of an expressed sequence tag library from Taenia solium, CysticercaIntegrated dataset of screening hits against multiple neglected disease pathogensIn-silico investigation of antitrypanosomal phytochemicals from Nigerian medicinal plantsComparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidatesExoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compoundsIdentification and characterization of potential therapeutic candidates in emerging human pathogen Mycobacterium abscessus: a novel hierarchical in silico approachThe open access malaria box: a drug discovery catalyst for neglected diseasesChemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasisApplication of RNAi to Genomic Drug Target Validation in SchistosomesA Multilayer Network Approach for Guiding Drug Repositioning in Neglected DiseasesDrug discovery and the use of computational approaches for infectious diseases.Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery.A Computational Methodology to Overcome the Challenges Associated With the Search for Specific Enzyme Targets to Develop Drugs Against Leishmania major.High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome.Two-stage flux balance analysis of metabolic networks for drug target identification.Cestode genomics - progress and prospects for advancing basic and applied aspects of flatworm biology.A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, Brugia malayi.Expression profile of the Schistosoma japonicum degradome reveals differential protease expression patterns and potential anti-schistosomal intervention targets.Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment.A genomic scale map of genetic diversity in Trypanosoma cruzi.Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets.A systems biological view of intracellular pathogensIdentification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection.Insights into the functional biology of schistosomesIn-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery.Proteome scale comparative modeling for conserved drug and vaccine targets identification in Corynebacterium pseudotuberculosisSchistosoma comparative genomics: integrating genome structure, parasite biology and anthelmintic discovery.Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis.Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum.Identification of Immunodominant B-cell Epitope Regions of Reticulocyte Binding Proteins in Plasmodium vivax by Protein Microarray Based Immunoscreening.In vivo-validated essential genes identified in Acinetobacter baumannii by using human ascites overlap poorly with essential genes detected on laboratory media.Drug Target Exploitable Structural Features of Adenylyl Cyclase Activity in Schistosoma mansoniMultiplex proteomics analysis of gender-associated proteins in Brugia malayiFunctional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoniIn silico prediction of antimalarial drug target candidates.Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps.Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection.
P2860
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P2860
Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of attractive d ...... ns using an in silico approach
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Identification of attractive d ...... ns using an in silico approach
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Identification of attractive d ...... ns using an in silico approach
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Identification of attractive d ...... ns using an in silico approach
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type
label
Identification of attractive d ...... ns using an in silico approach
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Identification of attractive d ...... ns using an in silico approach
@en
Identification of attractive d ...... ns using an in silico approach
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Identification of attractive d ...... ns using an in silico approach
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altLabel
Identification of Attractive D ...... ns Using an In Silico Approach
@en
prefLabel
Identification of attractive d ...... ns using an in silico approach
@ast
Identification of attractive d ...... ns using an in silico approach
@en
Identification of attractive d ...... ns using an in silico approach
@en-gb
Identification of attractive d ...... ns using an in silico approach
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P2093
P2860
P50
P921
P1476
Identification of attractive d ...... ns using an in silico approach
@en
P2093
Dhanasekaran Shanmugam
Maria A Doyle
Solomon Nwaka
P2860
P356
10.1371/JOURNAL.PNTD.0000804
P407
P50
P577
2010-01-01T00:00:00Z