about
P688
The nature of antioxidant defense mechanisms: a lesson from transgenic studiesMicroflora trigger colitis in mice deficient in selenium-dependent glutathione peroxidase and induce Gpx2 gene expressionKnockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stressDevelopmental changes in murine brain antioxidant enzymesTargeted mutation of the gene for cellular glutathione peroxidase (Gpx1) increases noise-induced hearing loss in mice.Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell deathGlutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injuryLow glutathione peroxidase activity in Gpx1 knockout mice protects jejunum crypts from gamma-irradiation damageGenetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cellsMultiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stressMice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineThe Gpx1 gene encodes mitochondrial glutathione peroxidase in the mouse liverSelenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids, and proteinEffects of dietary iron overload on glutathione peroxidase knockout miceCellular glutathione peroxidase deficiency and endothelial dysfunctionRedox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenaseImpaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunctionGlutathione-peroxidase-1 null muscle progenitor cells are globally defectiveNormal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1)Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizuresDiminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell deathSelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like familyHeterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structureKidney expression of glutathione peroxidase-1 is not protective against streptozotocin-induced diabetic nephropathyOpposite roles of selenium-dependent glutathione peroxidase-1 in superoxide generator diquat- and peroxynitrite-induced apoptosis and signalingMice with combined disruption of Gpx1 and Gpx2 genes have colitisIncreased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injuryThe effect of aging on glutathione peroxidase-i knockout mice-resistance of the lens to oxidative stressMitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 geneRetinal light damage: structural and functional effects of the antioxidant glutathione peroxidase-1Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia.
P921
Q24682324-FF40143A-C9C2-4D27-96FD-F81BDF206A32Q28204598-C8AC58EA-BC55-47AB-B4D4-FE8DD574BA63Q28372953-9D966935-12F5-4673-9133-60E774DA5ECFQ28505605-73DF1B1B-4D63-45AD-BB11-AD3D2C93DB7BQ28505958-63EE96CE-DDFA-4F71-BC61-EA9496F2CBC7Q28506873-413D21CF-5D46-403E-9571-E390157C191DQ28507903-DB15FC28-781F-4C30-B3A8-9AB2614C5BB5Q28508678-E51E7D52-8DBD-4793-89ED-448B8757BD6EQ28508696-185EE4B6-1301-409B-8E7C-DE546FFF6CC7Q28509555-ECF7DB2A-25C9-4540-8351-EDD0AA04CC8CQ28510205-39835BB0-1144-486D-AC51-E474E06E1ECAQ28510597-6E1F50F2-6D7C-42B2-AE6A-993439414CFFQ28510645-C31399C3-798B-4C69-9DA2-E4C86CD4C4A1Q28512892-F1DF0A10-77AB-4A02-A221-38AA8E0F12B1Q28513107-66987B25-052A-442C-BB05-EA5219FEE5CBQ28513921-C1E3B0FF-16F9-409D-B374-104696648BC0Q28586372-8405D952-EDF3-404A-B6C1-42F4A1F340D0Q28587484-86BB0F80-389A-488D-8024-31F349D687F9Q28589090-C8393400-8A7D-47F1-BB6F-64D1BDC58651Q28590477-1ADE0A7D-60A1-4E42-95F6-CB78CAA4A78FQ28591081-291D3B34-B10E-4A90-B218-46675633FE5DQ28591945-B3B02023-6590-4806-BAC8-498358E9DBAEQ28592048-AD9B2ECB-2391-4F23-AFFE-769EF9602F4FQ28592666-F2B35569-3D24-4FCE-8750-78A00727F886Q28593124-FEBD250E-A906-45F4-BDEF-69213DFBDC38Q28593227-E5FAE208-0037-4B99-9256-693551451A06Q28593399-F908BBA2-709E-4A73-9001-DD5255B918EBQ28593526-56835E6D-630C-4FA0-8478-87943B4229D7Q28593572-AAB16682-E998-4230-A2B3-2B9B1CFE1184Q28593999-F90ACDF1-22FC-404F-977A-C3AB669128D5Q34430043-EC5F20A0-BAAC-4994-900D-2A87CE4CB339
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Glutathione peroxidase 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Glutathione peroxidase 1
@en
type
label
Glutathione peroxidase 1
@en
altLabel
Gpx1
@en
cellular glutathione peroxidase
@en
glutathione peroxidase 1
@en
selenium-dependent glutathione peroxidase 1
@en
prefLabel
Glutathione peroxidase 1
@en
P637
P680
P681
P682
P705
P352
P279
P31
P352
P637
NP_001316456
NP_001316457
P680
P682
P702
P703
P705
ENSMUSP00000081010
ENSMUSP00000141279
ENSMUSP00000142257