A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2
about
FAT10, a ubiquitin-independent signal for proteasomal degradationExpression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancersConservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimerFAT10 plays a role in the regulation of chromosomal stabilityNEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradationThe ubiquitin-like protein FAT10 mediates NF-kappaB activationA novel protein-conjugating system for Ufm1, a ubiquitin-fold modifierThe UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1Characterization of clustered MHC-linked olfactory receptor genes in human and mouseSpecific association of estrogen receptor beta with the cell cycle spindle assembly checkpoint protein, MAD2Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyModification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysGene profiling, biomarkers and pathways characterizing HCV-related hepatocellular carcinomaPleiotropic effects of ATP.Mg2+ binding in the catalytic cycle of ubiquitin-activating enzymeFAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differencesUbiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenaseProfiling and selection of genes differentially expressed in the pylorus of rat strains with different proliferative responses and stomach cancer susceptibilityThe ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosisUbiquitin and ubiquitin-like proteins as multifunctional signalsDisruption of FAT10-MAD2 binding inhibits tumor progression.Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis.The role of cytokines in UbD promoter regulation and Mallory-Denk body-like aggresomesThe inherited blindness protein AIPL1 regulates the ubiquitin-like FAT10 pathwayUbiquitin D is correlated with colon cancer progression and predicts recurrence for stage II-III disease after curative surgery.Identification of a novel binding protein of FAT10: eukaryotic translation elongation factor 1A1.Regulation of apoptosis by fau revealed by functional expression cloning and antisense expression.Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation.FAT10, a gene up-regulated in various cancers, is cell-cycle regulated.FAT10 modifies p53 and upregulates its transcriptional activity.FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination.Ubiquitin-like protein activation.Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity.Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage displayUbiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platformProfiling of ubiquitin-like modifications reveals features of mitotic control.Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta CellsFAT10 is associated with the malignancy and drug resistance of non-small-cell lung cancerFAT10 level in human gastric cancer and its relation with mutant p53 level, lymph node metastasis and TNM stagingNodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease?
P2860
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P2860
A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@ast
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en-gb
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@nl
type
label
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@ast
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en-gb
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@nl
prefLabel
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@ast
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en-gb
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@nl
P2093
P2860
P3181
P356
P1476
A MHC-encoded ubiquitin-like p ...... sembly checkpoint protein MAD2
@en
P2093
J R Bender
M Collinge
S M Weissman
P2860
P304
P3181
P356
10.1073/PNAS.96.8.4313
P407
P577
1999-04-13T00:00:00Z