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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

http://www.wikidata.org/entity/Q22242282

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The roles of entropy and kinetics in structure prediction Sampling realistic protein conformations using local structural bias Experimental illumination of a fitness landscape Fundamental challenges in mechanistic enzymology: progress toward understanding the rate enhancements of enzymes Doing molecular biophysics: finding, naming, and picturing signal within complexity De novo computational design of retro-aldol enzymes Paradigms for computational nucleic acid design High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design Improved prediction of protein side-chain conformations with SCWRL4 Critical assessment of methods of protein structure prediction-Round VII High-resolution structure prediction and the crystallographic phase problem Computational design of Candida boidinii xylose reductase for altered cofactor specificity A composite score for predicting errors in protein structure models Design of protein-ligand binding based on the molecular-mechanics energy model RosettaDesign server for protein design Practical lessons from protein structure prediction.CAMPO, SCR_FIND and CHC_FIND: a suite of web tools for computational structural biology.Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design.Assessing local structural perturbations in proteins Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and Dynamics From Mollusks to Medicine: A Venomics Approach for the Discovery and Characterization of Therapeutics from Terebridae Peptide Toxins Why reinvent the wheel? Building new proteins based on ready-made parts Protein stability: computation, sequence statistics, and new experimental methods Self-assembled bionanostructures: proteins following the lead of DNA nanostructures Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics Urzymology: experimental access to a key transition in the appearance of enzymes Protein design: toward functional metalloenzymes Computational modeling of membrane proteins Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene Folding and Stabilization of Native-Sequence-Reversed Proteins.Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold Optimization Structure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding Affinities Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease Structure of a designed, right-handed coiled-coil tetramer containing all biological amino acids High-resolution design of a protein loop Improving NMR protein structure quality by Rosetta refinement: A molecular replacement study Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design Alteration of enzyme specificity by computational loop remodeling and design A Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family

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P2860

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

http://www.wikidata.org/entity/Q22242282

description

2003 nî lūn-bûn

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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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type

label

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

@ast

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

@en

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a novel globular protein fold with atomic-level accuracy

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prefLabel

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

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Design of a novel globular protein fold with atomic-level accuracy

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Barry L Stoddard

http://www.w3.org/2001/XMLSchema#string

Brian Kuhlman

http://www.w3.org/2001/XMLSchema#string

Gabriele Varani

http://www.w3.org/2001/XMLSchema#string

Gregory C Ireton

http://www.w3.org/2001/XMLSchema#string

P2860

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Native protein sequences are close to optimal for their structures

Improved methods for building protein models in electron density maps and the location of errors in these models

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Solution structure and dynamics of a designed hydrophobic core variant of ubiquitin

Side-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coils

Accurate computer-based design of a new backbone conformation in the second turn of protein L

De novo protein design: fully automated sequence selection

Design, structure and stability of a hyperthermophilic protein variant

High-resolution protein design with backbone freedom

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1364-1368

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10.1126/SCIENCE.1089427

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14631033

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protein folding