Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4
about
Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombinA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisSolution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinityEpiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis model.Factor Xa induces mitogenesis of vascular smooth muscle cells via autocrine production of epiregulinTumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2Src family kinases and HER2 interactions in human breast cancer cell growth and survival.The type 1 growth factor receptor family: new ligands and receptors and their role in breast cancer.Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of EpiregulinTake your partners, please--signal diversification by the erbB family of receptor tyrosine kinases.Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma.Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells.Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer.Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.Cholesteatoma fibroblasts promote epithelial cell proliferation through overexpression of epiregulin.High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor.The effect of epiregulin on epidermal growth factor receptor expression and proliferation of oral squamous cell carcinoma cell lines.Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor.Differences in genetic signaling, and not mechanical properties of the wall, are linked to ascending aortic aneurysms in fibulin-4 knockout miceCUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancyA role for the aryl hydrocarbon receptor in mammary gland tumorigenesis.c-erbB-4 protein expression in human breast cancerExpression and clinical significance of erb-B receptor family in hepatocellular carcinoma.Transformation of polarized epithelial cells by apical mistrafficking of epiregulinAutocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma.Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage.Autocrine-derived epidermal growth factor receptor ligands contribute to recruitment of tumor-associated macrophage and growth of basal breast cancer cells in vivo.Targeting the epidermal growth factor receptor in solid tumor malignancies.Epiregulin: roles in normal physiology and cancerEGFR-AKT-mTOR activation mediates epiregulin-induced pleiotropic functions in cultured osteoblasts.Epiregulin promotes the emergence and proliferation of adult liver progenitor cells.Epiregulin induces human SK-N-BE cell differentiation through ERK1/2 signaling pathway.Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.Toll-like receptor 4 differentially regulates epidermal growth factor-related growth factors in response to intestinal mucosal injury.Anti-EGFR monoclonal antibodies which act as EGF, TGF alpha, HB-EGF and BTC antagonists block the binding of epiregulin to EGFR-expressing tumours.Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES.Differential display and suppressive subtractive hybridization used to identify granulosa cell messenger rna associated with bovine oocyte developmental competence.Biochemical and functional analysis of smallpox growth factor (SPGF) and anti-SPGF monoclonal antibodies.
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P2860
Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tyrosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@ast
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en-gb
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@nl
type
label
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@ast
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en-gb
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@nl
prefLabel
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@ast
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en-gb
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@nl
P2093
P921
P356
P1433
P1476
Epiregulin binds to epidermal ...... tor, ErbB-2, ErbB-3 and ErbB-4
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1201458
P407
P577
1997-12-04T00:00:00Z
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P6179
1053429323