Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene
about
Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channelExpression of PKD1 and PKD2 transcripts and proteins in human embryo and during normal kidney developmentTrafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulationA polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesThe functions of TRPP2 in the vascular systemA polycystin-centric view of cyst formation and disease: the polycystins revisitedPolycystin-1: a master regulator of intersecting cystic pathwaysNedd9 restrains renal cystogenesis in Pkd1-/- miceCardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 geneNative polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epitheliaThe cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel FunctionA pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7Exon sequencing of PKD1 gene in an Iranian patient with autosomal-dominant polycystic kidney disease.Receptor protein tyrosine phosphatases are novel components of a polycystin complexNovel functional complexity of polycystin-1 by GPS cleavage in vivo: role in polycystic kidney diseaseExpression and distribution of transient receptor potential (TRP) channels in bladder epithelium.Intracellular calcium release modulates polycystin-2 trafficking.The versatile nature of the calcium-permeable cation channel TRPP2Aurora A kinase activity influences calcium signaling in kidney cells.Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney diseaseFibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.Distinct protein domains regulate ciliary targeting and function of C. elegans PKD-2.TRPpathies.Polycystin-2 immunolocalization and function in zebrafishCiliary dysfunction in polycystic kidney disease: an emerging model with polarizing potentialFunction and regulation of TRPP2 at the plasma membrane.Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2.Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease.The role of transient receptor potential cation channels in Ca2+ signalingNovel therapeutic approaches to autosomal dominant polycystic kidney disease.Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease.Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.A transcriptional network in polycystic kidney disease.Autosomal Dominant Polycystic Kidney Patients May Be Predisposed to Various Cardiomyopathies.Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries.
P2860
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P2860
Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Cellular and subcellular distr ...... otein product of the PKD2 gene
@ast
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en-gb
Cellular and subcellular distr ...... otein product of the PKD2 gene
@nl
type
label
Cellular and subcellular distr ...... otein product of the PKD2 gene
@ast
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en-gb
Cellular and subcellular distr ...... otein product of the PKD2 gene
@nl
prefLabel
Cellular and subcellular distr ...... otein product of the PKD2 gene
@ast
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en-gb
Cellular and subcellular distr ...... otein product of the PKD2 gene
@nl
P2093
P921
P1476
Cellular and subcellular distr ...... otein product of the PKD2 gene
@en
P2093
L Foggensteiner
O Ibraghimov-Beskrovnaya
R Sandford
P304
P407
P577
2000-05-01T00:00:00Z