The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP
about
Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interactionMembrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctionsRA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activationNedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEFThe guanine nucleotide exchange factor CNrasGEF regulates melanogenesis and cell survival in melanoma cellsRapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cellsThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonDirect binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activationThe M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytesThe Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptorProtein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropinProtein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: role of Epac IRap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activationIdentification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligasePhosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson diseaseSemaphorin 3A induces CaV2.3 channel-dependent conversion of axons to dendrites.Ras binding triggers ubiquitination of the Ras exchange factor Ras-GRF2.Identification of four candidate cGMP targets in DictyosteliumTargeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway.Small G protein signaling in neuronal plasticity and memory formation: the specific role of ras family proteinsPKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport.Search for new cyclic AMP-binding proteins.cAMP effector mechanisms. Novel twists for an 'old' signaling system.The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture.Signaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor.Role of beta-adrenoceptor signaling in skeletal muscle: implications for muscle wasting and disease.Separate cyclic AMP sensors for neuritogenesis, growth arrest, and survival of neuroendocrine cells.Biological roles of cAMP: variations on a theme in the different kingdoms of life.Thyrotropin regulates IL-6 expression in CD34+ fibrocytes: clear delineation of its cAMP-independent actions.Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics.cAMP-Induced Histones H3 Dephosphorylation Is Independent of PKA and MAP Kinase Activations and Correlates With mTOR Inactivation.Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.Gbetagamma dimers released in response to thyrotropin activate phosphoinositide 3-kinase and regulate gene expression in thyroid cells.Rap1 signaling in endothelial barrier control.Mechanism by which cAMP activates PI3-kinase and increases bile acid secretion in WIF-B9 cells.Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrityQuantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells.
P2860
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P2860
The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP
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2000 nî lūn-bûn
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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@ast
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en-gb
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@nl
type
label
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@ast
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en-gb
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@nl
prefLabel
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@ast
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en-gb
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@nl
P2093
P1433
P1476
The guanine nucleotide exchang ...... s in response to cAMP and cGMP
@en
P2093
P356
10.1016/S0960-9822(00)00473-5
P407
P577
2000-05-04T00:00:00Z