Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation - Wikidata - wikimedia - TriplyDB

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

http://www.wikidata.org/entity/Q28584307

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Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle alpha2C-adrenoceptors Radixin assembles cAMP effectors Epac and PKA into a functional cAMP compartment: role in cAMP-dependent cell proliferation Cell physiology of cAMP sensor Epac.The Epac1 signaling pathway regulates Cl- secretion via modulation of apical KCNN4c channels in diarrhea Rap1 activation is required for Fc gamma receptor-dependent phagocytosis Renal expression of exchange protein directly activated by cAMP (Epac) 1 and 2 Downregulation of Rap1GAP contributes to Ras transformation Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation Dissecting the mechanism of Epac activation via hydrogen-deuterium exchange FT-IR and structural modeling.The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edge Radil controls neutrophil adhesion and motility through β2-integrin activation.Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.Activation of MEK/ERK Signaling by PACAP in Guinea Pig Cardiac Neurons.Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Regulation of PC12 cell differentiation by cAMP signaling to ERK independent of PKA: do all the connections add up?A cAMP-dependent, protein kinase A-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells.Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.Activation of exchange protein activated by cyclic-AMP enhances long-lasting synaptic potentiation in the hippocampus Epac and PKA: a tale of two intracellular cAMP receptors.Dynamically driven ligand selectivity in cyclic nucleotide binding domains.The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.Prostaglandin E2 induces matrix metalloproteinase 9 expression in dendritic cells through two independent signaling pathways leading to activator protein 1 (AP-1) activation.Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.Regulation of Sertoli-germ cell adhesion and sperm release by FSH and nonclassical testosterone signaling.Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.Signaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor.Multiplexing PKA and ERK1&2 kinases FRET biosensors in living cells using single excitation wavelength dual colour FLIM.Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice.Differential effects of formoterol on thrombin- and PDGF-induced proliferation of human pulmonary arterial vascular smooth muscle cells.G protein regulation of MAPK networks.Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2 Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migration

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Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

http://www.wikidata.org/entity/Q28584307

description

2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2006

@ast

im März 2006 veröffentlichter wissenschaftlicher Artikel

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scientific journal article

@en

vedecký článok (publikovaný 2006/03/01)

@sk

vědecký článek publikovaný v roce 2006

@cs

wetenschappelijk artikel (gepubliceerd op 2006/03/01)

@nl

наукова стаття, опублікована в березні 2006

@uk

مقالة علمية (نشرت في مارس 2006)

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name

Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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MCB.26.6.2130-2145.2006

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Molecular and Cellular Biology

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Rap1-mediated activation of ex ...... on the mode of Rap1 activation

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Brian Hunter

http://www.w3.org/2001/XMLSchema#string

Kirstin Labudda

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Philip J. S. Stork

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Snigdha Mishra

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Tara J. Dillon

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Viji Pokala

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Zhiping Wang

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P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

A family of cAMP-binding proteins that directly activate Rap1

The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras

The guanine nucleotide exchange factor CNrasGEF regulates melanogenesis and cell survival in melanoma cells

The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane

Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

A ras-related gene with transformation suppressor activity

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

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2130–2145

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scholarly article

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3666378

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10.1128/MCB.26.6.2130-2145.2006

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6

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26

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16507992

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1430276

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