Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
about
Brick by brick: metabolism and tumor cell growthHuman papilloma viruses and cervical tumours: mapping of integration sites and analysis of adjacent cellular sequencesDysregulated metabolism contributes to oncogenesisMitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolismDetermination of phosphate-activated glutaminase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry)Co-expression of glutaminase K and L isoenzymes in human tumour cellsSilencing of GLS and overexpression of GLS2 genes cooperate in decreasing the proliferation and viability of glioblastoma cellsInterferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disordersMammalian glutaminase Gls2 gene encodes two functional alternative transcripts by a surrogate promoter usage mechanism.Complexity and species variation of the kidney-type glutaminase gene.Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegenerationA novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.From Krebs to clinic: glutamine metabolism to cancer therapy.Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells.MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer.Network of brain protein level changes in glutaminase deficient fetal miceSmall angle X-ray scattering studies of mitochondrial glutaminase C reveal extended flexible regions, and link oligomeric state with enzyme activity.Potentiation of Excitotoxicity in HIV-1 Associated Dementia and the Significance of Glutaminase.Effect of lysine to alanine mutations on the phosphate activation and BPTES inhibition of glutaminaseGlutaminase dysregulation in HIV-1-infected human microglia mediates neurotoxicity: relevant to HIV-1-associated neurocognitive disorders.Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibitionGlutaminase-containing microvesicles from HIV-1-infected macrophages and immune-activated microglia induce neurotoxicity.Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth.Inhibition of mitochondrial glutaminase activity reverses acquired erlotinib resistance in non-small cell lung cancerDibenzophenanthridines as inhibitors of glutaminase C and cancer cell proliferation.CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.In vitro glutaminase regulation and mechanisms of glutamate generation in HIV-1-infected macrophage.Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic targetGlutaminase regulation in cancer cells: a druggable chain of events.Therapeutic strategies impacting cancer cell glutamine metabolism.Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy.Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis.Tumour-Derived Glutamate: Linking Aberrant Cancer Cell Metabolism to Peripheral Sensory Pain PathwaysTargeting amino acid metabolism for cancer therapy.Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease.Glutaminase isoform expression in cell lines derived from human colorectal adenomas and carcinomas.Targeting glutamine uptake in AMLGenomic organization and transcriptional analysis of the human l-glutaminase gene.
P2860
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P2860
Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cloning and analysis of unique ...... -specific alternative splicing
@ast
Cloning and analysis of unique ...... -specific alternative splicing
@en
Cloning and analysis of unique ...... -specific alternative splicing
@en-gb
Cloning and analysis of unique ...... -specific alternative splicing
@nl
type
label
Cloning and analysis of unique ...... -specific alternative splicing
@ast
Cloning and analysis of unique ...... -specific alternative splicing
@en
Cloning and analysis of unique ...... -specific alternative splicing
@en-gb
Cloning and analysis of unique ...... -specific alternative splicing
@nl
prefLabel
Cloning and analysis of unique ...... -specific alternative splicing
@ast
Cloning and analysis of unique ...... -specific alternative splicing
@en
Cloning and analysis of unique ...... -specific alternative splicing
@en-gb
Cloning and analysis of unique ...... -specific alternative splicing
@nl
P2093
P1476
Cloning and analysis of unique ...... specific alternative splicing.
@en
P2093
P356
10.1152/PHYSIOLGENOMICS.1999.1.2.51
P407
P577
1999-08-31T00:00:00Z