Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr
about
Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditionsFunctional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemiaLoss-of-function mutations in APOC3, triglycerides, and coronary diseaseRecent progress in understanding protein and lipid factors affecting hepatic VLDL assembly and secretion.Genetic determinants of plasma triglyceridesD25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile.A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets.Aromatic residues in the C terminus of apolipoprotein C-III mediate lipid binding and LPL inhibition.Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL.Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation.The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation.
P2860
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P2860
Characterization of the lipid-binding properties and lipoprotein lipase inhibition of a novel apolipoprotein C-III variant Ala23Thr
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@ast
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@en
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@en-gb
Characterization of the lipid- ...... protein C-III variant Ala23Thr
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type
label
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@ast
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@en
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@en-gb
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@nl
prefLabel
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@ast
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@en
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@en-gb
Characterization of the lipid- ...... protein C-III variant Ala23Thr
@nl
P2093
P921
P1476
Characterization of the lipid- ...... protein C-III variant Ala23Thr
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P2093
M Rosseneu
P J Talmud
R Brasseur
S E Humphries
P304
P407
P577
2000-11-01T00:00:00Z