Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
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Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synucleinp25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathiesSecondary structure and dynamics of micelle bound beta- and gamma-synucleinResidual structure, backbone dynamics, and interactions within the synuclein familyFunction and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescenceThe Synaptic Function of α-SynucleinClustering of alpha-synuclein on supported lipid bilayers: role of anionic lipid, protein, and divalent ion concentrationMOAG-4 promotes the aggregation of α-synuclein by competing with self-protective electrostatic interactions.Methionine oxidation stabilizes non-toxic oligomers of alpha-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions.{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics.Annular arrangement and collaborative actions of four domains of protein-disulfide isomerase: a small angle X-ray scattering study in solution.A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation.Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies.Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calciumTranslocation of alpha-synuclein expressed in Escherichia coli.The Interplay between Alpha-Synuclein Clearance and Spreadingα-synuclein-lanthanide metal ions interaction: binding sites, conformation and fibrillationPhysiological phenotype and vulnerability in Parkinson's diseaseCalcium(II) selectively induces alpha-synuclein annular oligomers via interaction with the C-terminal domainMetabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein.Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases.Advances in lanthanide-based luminescent peptide probes for monitoring the activity of kinase and phosphatase.Interactions between calcium and alpha-synuclein in neurodegeneration.Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous roleProtein Partners of α-Synuclein in Health and Disease.Calcium and Parkinson's disease.Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies.Cell Biology and Pathophysiology of α-Synuclein.Potassium depolarization and raised calcium induces α-synuclein aggregates.Comparative analysis of different peptidyl-prolyl isomerases reveals FK506-binding protein 12 as the most potent enhancer of alpha-synuclein aggregation.NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.The role of the acidic domain of α-synuclein in amyloid fibril formation: a molecular dynamics study.SERF protein is a direct modifier of amyloid fiber assembly.Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non-fibrillar amyloid: a link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)?Allostery in a disordered protein: oxidative modifications to α-synuclein act distally to regulate membrane binding.Molecular Role of Ca2+ and Hard Divalent Metal Cations on Accelerated Fibrillation and Interfibrillar Aggregation of α-Synuclein.C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes.
P2860
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P2860
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@ast
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en-gb
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@nl
type
label
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@ast
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en-gb
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@nl
prefLabel
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@ast
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en-gb
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@nl
P2860
P921
P356
P1476
Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization
@en
P2093
P2860
P304
22680-22684
P356
10.1074/JBC.M101181200
P407
P577
2001-04-18T00:00:00Z