The herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domain
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Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5US11 of herpes simplex virus type 1 interacts with HIPK2 and antagonizes HIPK2-induced cell growth arrestInhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein.Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionAssociation of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptidesWho Regulates Whom? An Overview of RNA Granules and Viral InfectionsAlphaherpesvirus Subversion of Stress-Induced Translational ArrestCoronavirus gene 7 counteracts host defenses and modulates virus virulenceVaricella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3Herpes simplex virus 2 infection impacts stress granule accumulationHuman Herpesvirus 6A Exhibits Restrictive Propagation with Limited Activation of the Protein Kinase R-eIF2α Stress Pathway.Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.Dysregulation of autophagy in murine fibroblasts resistant to HSV-1 infectionIn vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation.Herpesviruses and autophagy: catch me if you can!Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes.RNA binding properties of the US11 protein from four primate simplexvirusesNeutralizing innate host defenses to control viral translation in HSV-1 infected cells.Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.Varicella-Zoster virus IE63, a major viral latency protein, is required to inhibit the alpha interferon-induced antiviral responseViruses with deletions in antiapoptotic genes as potential oncolytic agents.The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.Expression of gamma interferon-dependent genes is blocked independently by virion host shutoff RNase and by US3 protein kinaseRole of indoleamine-2,3-dioxygenase in alpha/beta and gamma interferon-mediated antiviral effects against herpes simplex virus infections.Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectorsRecognition of herpes simplex viruses: toll-like receptors and beyondHerpes simplex virus oncolytic vaccine therapy in melanoma.Oncolytic HSV-1 virotherapy: clinical experience and opportunities for progressSpontaneous and Engineered Compensatory HSV Mutants that Counteract the Host Antiviral PKR Response.Herpesviruses: interfering innate immunity by targeting viral sensing and interferon pathways.Herpes Simplex Virus 2 Virion Host Shutoff Endoribonuclease Activity Is Required To Disrupt Stress Granule Formation.Herpes simplex virus type 1 virion-derived US11 inhibits type 1 interferon-induced protein kinase R phosphorylation.Expression, purification of herpes simplex virus type 1 US11 protein, and production of US11 polyclonal antibody.The IE180 protein of pseudorabies virus suppresses phosphorylation of translation initiation factor eIF2α.Characterization of RNA determinants recognized by the arginine- and proline-rich region of Us11, a herpes simplex virus type 1-encoded double-stranded RNA binding protein that prevents PKR activation.Identification of a lytic-cycle Epstein-Barr virus gene product that can regulate PKR activation.The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation.OPTIM trial: a Phase III trial of an oncolytic herpes virus encoding GM-CSF for unresectable stage III or IV melanoma.Full resistance of herpes simplex virus type 1-infected primary human cells to alpha interferon requires both the Us11 and gamma(1)34.5 gene products.
P2860
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P2860
The herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domain
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The herpes simplex virus type ...... t to a kinase substrate domain
@ast
The herpes simplex virus type ...... t to a kinase substrate domain
@en
The herpes simplex virus type ...... t to a kinase substrate domain
@en-gb
The herpes simplex virus type ...... t to a kinase substrate domain
@nl
type
label
The herpes simplex virus type ...... t to a kinase substrate domain
@ast
The herpes simplex virus type ...... t to a kinase substrate domain
@en
The herpes simplex virus type ...... t to a kinase substrate domain
@en-gb
The herpes simplex virus type ...... t to a kinase substrate domain
@nl
prefLabel
The herpes simplex virus type ...... t to a kinase substrate domain
@ast
The herpes simplex virus type ...... t to a kinase substrate domain
@en
The herpes simplex virus type ...... t to a kinase substrate domain
@en-gb
The herpes simplex virus type ...... t to a kinase substrate domain
@nl
P2860
P3181
P1433
P1476
The herpes simplex virus type ...... t to a kinase substrate domain
@en
P2093
Kevin A Cassady
Martin Gross
P2860
P304
P3181
P356
10.1128/JVI.76.5.2029-2035.2002
P407
P577
2002-03-01T00:00:00Z