Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor
about
Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7Recent Progress in Therapeutic Treatments and Screening Strategies for the Prevention and Treatment of HPV-Associated Head and Neck CancerRegulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 OncoproteinsStructure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressorGenome stability pathways in head and neck cancersOrdered self-assembly mechanism of a spherical oncoprotein oligomer triggered by zinc removal and stabilized by an intrinsically disordered domainThe canine papillomavirus and gamma HPV E7 proteins use an alternative domain to bind and destabilize the retinoblastoma protein.Up-regulation of expression and lack of 5' CpG island hypermethylation of p16 INK4a in HPV-positive cervical carcinomas.The landscape of human proteins interacting with viruses and other pathogens.Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review.Retinoblastoma-independent antiproliferative activity of novel intracellular antibodies against the E7 oncoprotein in HPV 16-positive cellsComparative analysis of HPV16 gene expression profiles in cervical and in oropharyngeal squamous cell carcinoma.Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein.The nuclear localization of low risk HPV11 E7 protein mediated by its zinc binding domain is independent of nuclear import receptors.Use of cell-SELEX to generate DNA aptamers as molecular probes of HPV-associated cervical cancer cellsActivation of the retinoblastoma tumor suppressor mediates cell cycle inhibition and cell death in specific cervical cancer cell lines.Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model.Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor virusesSubcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ.Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients.Sequence evolution of the intrinsically disordered and globular domains of a model viral oncoprotein.The high-risk HPV16 E7 oncoprotein mediates interaction between the transcriptional coactivator CBP and the retinoblastoma protein pRb.Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damageAn RNA aptamer provides a novel approach for the induction of apoptosis by targeting the HPV16 E7 oncoprotein.Nonconserved lysine residues attenuate the biological function of the low-risk human papillomavirus E7 proteinConformational dissection of a viral intrinsically disordered domain involved in cellular transformation.Molecular cloning and characterisation of a novel type of human papillomavirus 160 isolated from a flat wart of an immunocompetent patientSystematic analysis of the amino acid residues of human papillomavirus type 16 E7 conserved region 3 involved in dimerization and transformation.Diversity and evolution of chromatin proteins encoded by DNA viruses.The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers.Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins.Molecular screening of compounds to the predicted Protein-Protein Interaction site of Rb1-E7 with p53- E6 in HPV.Novel Bovine Papillomavirus Type Discovered by Rolling-Circle Amplification Coupled with Next-Generation SequencingCancer associated human papillomaviruses.Conserved region 3 of human papillomavirus 16 E7 contributes to deregulation of the retinoblastoma tumor suppressor.Cellular binding partners of the human papillomavirus E6 protein.Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300Minute time scale prolyl isomerization governs antibody recognition of an intrinsically disordered immunodominant epitope
P2860
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P2860
Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@ast
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en-gb
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@nl
type
label
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@ast
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en-gb
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@nl
prefLabel
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@ast
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en-gb
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@nl
P2093
P2860
P3181
P356
P1476
Structure of the human Papillo ...... etinoblastoma tumor suppressor
@en
P2093
Adrienne Clements
Kehao Zhao
P2860
P304
P3181
P356
10.1074/JBC.M508455200
P407
P577
2006-01-06T00:00:00Z