about
Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with peptide substrateStructure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressorThe human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targetingA tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functionsCrystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complexThe structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domainInhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylasesStructure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assemblyStructure and mechanism of non-histone protein acetyltransferase enzymesThe catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediateStructure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activityStructure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitorCrystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulationStructure of a Sir2 substrate, Alba, reveals a mechanism for deacetylation-induced enhancement of DNA bindingStructure and autoregulation of the yeast Hst2 homolog of Sir2Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferaseStructure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptideMolecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substratesStructural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 EnzymesMolecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating EnzymeStructure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressorStructural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain ProteinThe structural basis of protein acetylation by the p300/CBP transcriptional coactivatorStructure-Based Design of an Organoruthenium Phosphatidyl-inositol-3-kinase Inhibitor Reveals a Switch Governing Lipid Kinase Potency and SelectivityFungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBPStructural Basis for Dimerization in DNA Recognition by Gal4Structure of Vps75 and implications for histone chaperone functionStructural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational ModificationTargeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium ComplexesThe Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF KinaseStructure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricusStructure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone AcetylationStructurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase InhibitorsStructure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific AcetylationThe Art of Filling Protein Pockets Efficiently with Octahedral Metal ComplexesIdentification of a Novel Family of BRAF V600E InhibitorsMolecular basis for N-terminal acetylation by the heterodimeric NatA complexImplications for the evolution of eukaryotic amino-terminal acetyltransferase (NAT) enzymes from the structure of an archaeal orthologFRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Ronen Marmorstein
@ast
Ronen Marmorstein
@en
Ronen Marmorstein
@es
Ronen Marmorstein
@sl
type
label
Ronen Marmorstein
@ast
Ronen Marmorstein
@en
Ronen Marmorstein
@es
Ronen Marmorstein
@sl
prefLabel
Ronen Marmorstein
@ast
Ronen Marmorstein
@en
Ronen Marmorstein
@es
Ronen Marmorstein
@sl