ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
about
SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activityFYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cellsFunctional association between SLAP-130 and SLP-76 in Jurkat T cellsFunctional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signalingRegulation of Fyn through translocation of activated Lck into lipid raftsTyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphataseDistinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytesStructural and functional studies of the intracellular tyrosine kinase MATK gene and its translated productMolecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signalingMolecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sitesMolecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytesMolecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytesCloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 productionFYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cellsMechanism of activation for Zap-70 catalytic activityAnalysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonanceInteraction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signalingThe kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localizationActivation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain moleculeIn vivo correction of ZAP-70 immunodeficiency by intrathymic gene transferIdentification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domainsGRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulationDistinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor functionBinding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteinsCustomized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemiaT cell activationMolecular mechanisms for adaptive tolerance and other T cell anergy modelsRIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activationRole of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signalingSyk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complexDifferent roles for the Fc epsilon RI gamma chain as a function of the receptor contextT cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)Signal transduction by immunoglobulin is mediated through Ig alpha and Ig betaAltered signalling thresholds in T lymphocytes cause autoimmune arthritisMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsDisturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus ErythematosusThe Role of Crk Adaptor Proteins in T-Cell Adhesion and MigrationAn immunology primer for computational modelersThymus, innate immunity and autoimmune arthritis: interplay of gene and environmentNovel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production
P2860
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P2860
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
description
1992 nî lūn-bûn
@nan
1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@ast
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en-gb
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@nl
type
label
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@ast
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en-gb
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@nl
prefLabel
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@ast
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en-gb
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@nl
P2093
P3181
P1433
P1476
ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
@en
P2093
P304
P3181
P356
10.1016/0092-8674(92)90598-7
P407
P577
1992-11-13T00:00:00Z