RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
about
Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cellsVEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis.LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activationVascular endothelial growth factor A: just one of multiple mechanisms for sex-specific vascular development within the testis?MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathwayCloning and characterization of ALX, an adaptor downstream of CD28T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells.Essential role of the T cell-specific adapter protein in the activation of LCK in peripheral T cells.VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.Differential role of SLP-76 domains in T cell development and functionThe Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via SrcItk: the rheostat of the T cell response.Reduced MCMV Δm157 viral clearance in the absence of TSAd.Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytesIdentification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice.A transcription function for the T cell-specific adapter (TSAd) protein in T cells: critical role of the TSAd Src homology 2 domain.Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient miceRole of Txk, a member of the Tec family of tyrosine kinases, in immune-inflammatory diseases.Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cellsHow diverse--CD4 effector T cells and their functions.VEGF receptor signaling in vertebrate development.The role of Tec family kinases in the regulation of T-helper-cell differentiation.Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX.The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein.Modulation of Lck function through multisite docking to T cell-specific adapter protein.The carboxyl-terminal segment of the adaptor protein ALX directs its nuclear export during T cell activation.The ALX Src homology 2 domain is both necessary and sufficient to inhibit T cell receptor/CD28-mediated up-regulation of RE/AP.Th1-dominant shift of T cell cytokine production, and subsequent reduction of serum immunoglobulin E response by administration in vivo of plasmid expressing Txk/Rlk, a member of Tec family tyrosine kinases, in a mouse model.Expression of the T cell-specific adapter protein in human tissues.CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein.The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation.The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
P2860
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P2860
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@ast
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@en
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@nl
type
label
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@ast
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@en
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@nl
prefLabel
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@ast
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@en
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@nl
P2093
P2860
P356
P1476
RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation
@en
P2093
A I Sperling
C L Sommers
D C Decker
E O Mitchell
J A Bluestone
K Rajagopal
U Korthauer
P2860
P304
P356
10.1084/JEM.190.11.1657
P407
P577
1999-12-06T00:00:00Z