Expression of cDNA encoding the human "protective protein" associated with lysosomal beta-galactosidase and neuraminidase: homology to yeast proteases
about
Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein/cathepsin A.Mutations in the human UDP-N-acetylglucosamine 2-epimerase gene define the disease sialuria and the allosteric site of the enzymeA mutation in a mild form of galactosialidosis impairs dimerization of the protective protein and renders it unstableMutations in the lysosomal beta-galactosidase gene that cause the adult form of GM1 gangliosidosisCharacterization of the yeast KEX1 gene product: a carboxypeptidase involved in processing secreted precursor proteinsCloning of a novel retinoid-inducible serine carboxypeptidase from vascular smooth muscle cellsRat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosisThe atomic model of the human protective protein/cathepsin A suggests a structural basis for galactosialidosis.Stable expression of protective protein/cathepsin A-green fluorescent protein fusion genes in a fibroblastic cell line from a galactosialidosis patient. Model system for revealing the intracellular transport of normal and mutated lysosomal enzymes.Towards a human repertoire of monocytic lysosomal proteins.Lysosomal multienzyme complex: pros and cons of working togetherCathepsin A deficiency in galactosialidosis: studies of patients and carriers in 16 families.Glycoproteomic analysis of glioblastoma stem cell differentiation.A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles.Molecular mechanisms of pathogenesis in a glycosphingolipid and a glycoprotein storage diseaseA genetic map of chromosome 20q12-q13.1: multiple highly polymorphic microsatellite and RFLP markers linked to the maturity-onset diabetes of the young (MODY) locusThe metabolic serine hydrolases and their functions in mammalian physiology and disease.Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serumProtective protein gene mutations in galactosialidosisVacuolar protein sorting in fission yeast: cloning, biosynthesis, transport, and processing of carboxypeptidase Y from Schizosaccharomyces pombe.Preclinical dose-finding study with a liver-tropic, recombinant AAV-2/8 vector in the mouse model of galactosialidosis.Correction of murine galactosialidosis by bone marrow-derived macrophages overexpressing human protective protein/cathepsin A under control of the colony-stimulating factor-1 receptor promoter.Mitochondrial Ca2+ homeostasis in lysosomal storage diseases.Serine carboxypeptidase 46 Regulates Grain Filling and Seed Germination in Rice (Oryza sativa L.).Chaperone-mediated gene therapy with recombinant AAV-PPCA in a new mouse model of type I sialidosisAberrant expression of sialidase and cancer progression.Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization.An extraovarian protein accumulated in mosquito oocytes is a carboxypeptidase activated in embryos.Remodeling natural products: chemistry and serine hydrolase activity of a rocaglate-derived β-lactone.Sialidase significance for cancer progression.Crystallization of a soluble form of the Kex1p serine carboxypeptidase from Saccharomyces cerevisiae.Galactosialidosis: historic aspects and overview of investigated and emerging treatment options.Sialylation of N-glycans: mechanism, cellular compartmentalization and function.Limited inhibitory effects of oseltamivir and zanamivir on human sialidasesSchizosaccharomyces pombe sxa1+ and sxa2+ encode putative proteases involved in the mating response.Processing of lysosomal beta-galactosidase. The C-terminal precursor fragment is an essential domain of the mature enzyme.Lysosomal protective protein/cathepsin A. Role of the "linker" domain in catalytic activation.Tumor progression and angiogenesis: cathepsin B & Co.Lysosomal Cathepsin A Plays a Significant Role in the Processing of Endogenous Bioactive Peptides.Characterization of three alleles causing aspartylglycosaminuria: two from a British family and one from an American patient.
P2860
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P2860
Expression of cDNA encoding the human "protective protein" associated with lysosomal beta-galactosidase and neuraminidase: homology to yeast proteases
description
1988 nî lūn-bûn
@nan
1988 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Expression of cDNA encoding th ...... e: homology to yeast proteases
@ast
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en-gb
Expression of cDNA encoding th ...... e: homology to yeast proteases
@nl
type
label
Expression of cDNA encoding th ...... e: homology to yeast proteases
@ast
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en-gb
Expression of cDNA encoding th ...... e: homology to yeast proteases
@nl
prefLabel
Expression of cDNA encoding th ...... e: homology to yeast proteases
@ast
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en-gb
Expression of cDNA encoding th ...... e: homology to yeast proteases
@nl
P2093
P3181
P1433
P1476
Expression of cDNA encoding th ...... e: homology to yeast proteases
@en
P2093
F W Verheijen
H Galjaard
N Gillemans
N J Galjart
P304
P3181
P356
10.1016/S0092-8674(88)90999-3
P407
P577
1988-09-01T00:00:00Z