The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's diseaseStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionUbiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatmentThe Function of Autophagy in Neurodegenerative DiseasesThe different facets of organelle interplay-an overview of organelle interactionsThe dynamics of the mitochondrial organelle as a potential therapeutic targetMitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorderThe pathways of mitophagy for quality control and clearance of mitochondriaRole of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.Mitochondrial dynamics and viral infections: A close nexusAutophagosome dynamics in neurodegeneration at a glanceMitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expressionEvidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson diseaseE3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumoniaBeyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial healthMacroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteinsPINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease.PINK1 is degraded through the N-end rule pathwayKeeping the immune system in check: a role for mitophagy.A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differentlyGlyGly-CTERM and rhombosortase: a C-terminal protein processing signal in a many-to-one pairing with a rhomboid family intramembrane serine proteaseProfiling the mitochondrial proteome of Leber's Hereditary Optic Neuropathy (LHON) in Thailand: down-regulation of bioenergetics and mitochondrial protein quality control pathways in fibroblasts with the 11778G>A mutationMitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial bindingTom70 is essential for PINK1 import into mitochondriaPINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondriaPhosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy.Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosisRole of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase ParkinNRF2 Regulates PINK1 Expression under Oxidative Stress Conditions.Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitmentMiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5The emerging role of proteolysis in mitochondrial quality control and the etiology of Parkinson's disease.
P2860
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P2860
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@ast
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en-gb
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@nl
type
label
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@ast
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en-gb
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@nl
prefLabel
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@ast
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en-gb
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@nl
P2093
P2860
P921
P3181
P1476
The mitochondrial intramembran ...... to regulate Pink1 trafficking
@en
P2093
Andreas Weihofen
Cathrin Meissner
Dennis J Selkoe
Holger Lorenz
P2860
P304
P3181
P356
10.1111/J.1471-4159.2011.07253.X
P407
P577
2011-06-01T00:00:00Z