APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks
about
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayAPLF promotes the assembly and activity of non-homologous end joining protein complexesSpecific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNKPhospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damageEukaryotic DNA ligases: structural and functional insightsSubstrate recognition and function of the R2TP complex in response to cellular stressDNA-PK: a dynamic enzyme in a versatile DSB repair pathwaySolution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)The role of ADP-ribosylation in regulating DNA interstrand crosslink repairADP-ribosyltransferases and poly ADP-ribosylationThe structural basis of XRCC1-mediated DNA repairX-ray repair cross complementing protein 1 in base excision repair.Nonhomologous end joining: a good solution for bad endsMolecular Insights into Poly(ADP-ribose) Recognition and Processing.Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complexMutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joiningNon-homologous end joining: emerging themes and unanswered questions.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeStructure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response.The role of ADP-ribosylation in regulating DNA double-strand break repairNon-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process.Histone chaperones in nucleosome assembly and human diseaseHuman RECQ1 interacts with Ku70/80 and modulates DNA end-joining of double-strand breaksIdentification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF)Mechanism and regulation of class switch recombinationRecognition and repair of chemically heterogeneous structures at DNA endsPARP regulates nonhomologous end joining through retention of Ku at double-strand breaksPhosphorylation-regulated binding of Ctp1 to Nbs1 is critical for repair of DNA double-strand breaksPolynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.Genome-wide screens for sensitivity to ionizing radiation identify the fission yeast nonhomologous end joining factor Xrc4.ATP-dependent chromatin remodeling in the DNA-damage response.APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.DNA repair factor APLF is a histone chaperone.The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sitesRegulation of AID, the B-cell genome mutator.Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin.DNA double strand break repair via non-homologous end-joining.Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein.Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.Cellular and sub-cellular responses to UVA in relation to carcinogenesis.
P2860
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P2860
APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@ast
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en-gb
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@nl
type
label
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@ast
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en-gb
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@nl
prefLabel
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@ast
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en-gb
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@nl
P2093
P2860
P3181
P356
P1476
APLF (C2orf13) is a novel huma ...... chromosomal DNA strand breaks
@en
P2093
Keith W Caldecott
Natasha Iles
Sherif F El-Khamisy
Stuart Rulten
P2860
P304
P3181
P356
10.1128/MCB.02269-06
P407
P577
2007-05-01T00:00:00Z