Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.

Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.

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http://www.wikidata.org/entity/Q35379148

Q35379148

about

APLF promotes the assembly and activity of non-homologous end joining protein complexes The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy Processing of damaged DNA ends for double-strand break repair in mammalian cells The structural basis of XRCC1-mediated DNA repair Role of non-homologous end joining in V(D)J recombination Nonhomologous end joining: a good solution for bad ends A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex Non-homologous end joining: emerging themes and unanswered questions.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.DNA double strand break repair via non-homologous end-joining.Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?Repair of double-strand breaks by end joining.Non-homologous end joining often uses microhomology: implications for alternative end joining.Understanding the DNA damage response in order to achieve desired gene editing outcomes in mosquitoes.Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease Effects of DNA end configuration on XRCC4-DNA ligase IV and its stimulation of Artemis activity.Coordination of DNA single strand break repair.Mechanisms of DNA damage, repair, and mutagenesis.TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.Nonhomologous DNA End Joining for Repair of DNA Double-Strand Breaks.

P2860

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P2860

Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.

Item

http://www.wikidata.org/entity/Q35379148

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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