The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
about
DJ-1 cleavage by matrix metalloproteinase 3 mediates oxidative stress-induced dopaminergic cell deathThe role of oxidative stress in Parkinson's diseaseOxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1DJ-1 induces thioredoxin 1 expression through the Nrf2 pathwayRNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathwaysHuman DJ-1 and its homologs are novel glyoxalasesMitochondrial localization of DJ-1 leads to enhanced neuroprotectionDJ-1 is a copper chaperone acting on SOD1 activationAdult Astrogenesis and the Etiology of Cortical NeurodegenerationNeuroinflammation in Parkinson's disease and its potential as therapeutic targetOxidative stress and Parkinson's diseaseThe role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structuresSerotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson's DiseaseAge-dependent motor deficits and dopaminergic dysfunction in DJ-1 null miceDJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE)The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS productionHypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.Parkinson's Disease and Cognitive ImpairmentDJ-1 Is Upregulated in Oral Squamous Cell Carcinoma and Promotes Oral Cancer Cell Proliferation and InvasionGenetic mouse models of parkinsonism: strengths and limitations.Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 geneBAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity.Mechanisms of Parkinson's disease-related proteins in mediating secondary brain damage after cerebral ischemia.Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption.DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.Immunostaining of oxidized DJ-1 in human and mouse brainsNeuroproteomics as a promising tool in Parkinson's disease research.DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1Parkinson's disease: Exit toxins, enter geneticsAstrocytes and therapeutics for Parkinson's disease.Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants.The genetics of Parkinson disease.The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localizationDJ-1 Mutations are Rare in a Swedish Parkinson CohortDJ-1 is activated in medulloblastoma and is associated with cell proliferation and differentiationMutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging.Astrocytic dynamin-like protein 1 regulates neuronal protection against excitotoxicity in Parkinson disease.
P2860
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P2860
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@ast
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en-gb
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@nl
type
label
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@ast
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en-gb
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@nl
prefLabel
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@ast
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en-gb
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@nl
P2093
P50
P921
P3181
P356
P1433
P1476
The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
@en
P2093
Alan M Pittman
Andrew D Hope
Andrew J Leonard
Andrew R Reid
Ann E Kingsbury
Catherine Strand
Chris McLendon
Daniel G Healy
David W Miller
Hiroyashi Ariga
P304
P3181
P356
10.1093/BRAIN/AWH054
P407
P577
2004-02-01T00:00:00Z