DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
about
DJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosisThe role of oxidative stress in Parkinson's diseaseDJ-1 induces thioredoxin 1 expression through the Nrf2 pathwayThe Tumorigenic Roles of the Cellular REDOX Regulatory SystemsParkinson's disease proteins: Novel mitochondrial targets for cardioprotectionTherapeutic targets in the ASK1-dependent stress signaling pathwaysConservation of oxidative protein stabilization in an insect homologue of parkinsonism-associated protein DJ-1Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimersCross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for CancerEffects of hyperoxia on cytoplasmic thioredoxin system in alveolar type epithelial cells of premature ratsData on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cellsBrain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption.Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.The role of cysteine oxidation in DJ-1 function and dysfunction.Thiol redox homeostasis in neurodegenerative diseaseRole of renal DJ-1 in the pathogenesis of hypertension associated with increased reactive oxygen species productionNeuroprotective Effect of the Marine-Derived Compound 11-Dehydrosinulariolide through DJ-1-Related Pathway in In Vitro and In Vivo Models of Parkinson's Disease.Oxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2.Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis.Computational genomic analysis of PARK7 interactome reveals high BBS1 gene expression as a prognostic factor favoring survival in malignant pleural mesothelioma.Down-Regulation of Thioredoxin1 Is Involved in Death of Calu-6 Lung Cancer Cells Treated With Suberoyl Bishydroxamic Acid.Redox signaling: An evolution from free radicals to agingUpregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation.Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease.Cytoprotective mechanisms of DJ-1 against oxidative stress through modulating ERK1/2 and ASK1 signal transduction.Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress.The Multifaceted Roles of DJ-1 as an Antioxidant.Regulation of Signal Transduction by DJ-1.Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt-Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress.DJ-1 as a Therapeutic Target Against Cancer.The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress
P2860
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P2860
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
@ast
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
@en
type
label
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
@ast
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
@en
prefLabel
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
@ast
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
@en
P2093
P2860
P1476
DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex
@en
P2093
Eunsung Junn
Joo-Young Im
Kang-Woo Lee
P2860
P304
P356
10.1016/J.NEURES.2010.04.002
P577
2010-04-10T00:00:00Z