Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
about
Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membraneOncogenic function of DACT1 in colon cancer through the regulation of β-cateninConstitutive activation of the Wnt canonical pathway in mantle cell lymphomaDeubiquitination of Dishevelled by Usp14 is required for Wnt signalingDACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modificationsIdentification of novel rare mutations of DACT1 in human neural tube defectsDapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleusProtein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradationWnt/beta-catenin signaling and small molecule inhibitorsDevelopment of anticancer agents targeting the Wnt/β-catenin signalingDapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneuronsSevere acute respiratory syndrome-associated coronavirus nucleocapsid protein interacts with Smad3 and modulates transforming growth factor-beta signalingThe association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiationEndofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signalingDisruption of the Dapper3 gene aggravates ureteral obstruction-mediated renal fibrosis by amplifying Wnt/β-catenin signalingDact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cellsDact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling networkPosterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streakLoss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in miceAll Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinasesRegulation of ciliary polarity by the APC/C.Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signalingRiding shotgun: a dual role for the epidermal growth factor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking.Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation.Pro-inflammatory wnt5a and anti-inflammatory sFRP5 are differentially regulated by nutritional factors in obese human subjects.Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia.Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer developmentAn unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle.Dact2 represses PITX2 transcriptional activation and cell proliferation through Wnt/beta-catenin signaling during odontogenesis.Retinoic acid negatively regulates dact3b expression in the hindbrain of zebrafish embryos.The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.Dact genes are chordate specific regulators at the intersection of Wnt and Tgf-β signaling pathwaysCytoplasmic HDPR1 is involved in regional lymph node metastasis and tumor development via beta-catenin accumulation in esophageal squamous cell carcinoma.The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy.Collagen Type I Improves the Differentiation of Human Embryonic Stem Cells towards Definitive EndodermTranscriptome response to heat stress in a chicken hepatocellular carcinoma cell line.Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradationDapper homolog 1 is a novel tumor suppressor in gastric cancer through inhibiting the nuclear factor-κB signaling pathway.DACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer.Reduced expression of DACT2 promotes hepatocellular carcinoma progression: involvement of methylation-mediated gene silencing
P2860
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P248
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P2860
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@ast
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en-gb
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@nl
type
label
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@ast
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en-gb
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@nl
prefLabel
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@ast
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en-gb
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@nl
P2093
P3181
P356
P1476
Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation
@en
P2093
Long Zhang
Ye-Guang Chen
Yuanheng Ning
P304
P3181
P356
10.1074/JBC.M600274200
P407
P577
2006-03-31T00:00:00Z