about
TIN2, a new regulator of telomere length in human cellsNuclear structure in normal and Bloom syndrome cellsTelomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumorsTelomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresThe telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complexInvolvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindleThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2Rap1 affects the length and heterogeneity of human telomeresPOT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexProtein requirements for sister telomere association in human cellsWRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shorteningTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationCharacterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosisIn vivo stoichiometry of shelterin componentsTelomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeatsTRF1 is a dimer and bends telomeric DNAHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroPOT1 and TRF2 cooperate to maintain telomeric integrityThe human telomere-associated protein TIN2 stimulates interactions between telomeric DNA tracts in vitroCell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeresThe telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and humanControl of human telomere length by TRF1 and TRF2Human telomerase contains evolutionarily conserved catalytic and structural subunitsFunctional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongationProlyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteinsStructure of the DNA-binding domain of NgTRF1 reveals unique features of plant telomere-binding proteinsA protein-counting mechanism for telomere length regulation in yeast.Rap1 prevents telomere fusions by nonhomologous end joining.MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length controlZscan4 regulates telomere elongation and genomic stability in ES cellsTRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeresNBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeresA human interstitial telomere associates in vivo with specific TRF2 and TIN2 proteinsTranscriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factorsMEN1 tumor-suppressor protein localizes to telomeres during meiosisTankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping
P2860
Q22010863-65062BE7-A207-4167-9AB4-6428B4959477Q22253976-13EF1032-0C7E-477C-B73C-19B52CA0FE9CQ24291157-E8AF78FD-1ED3-449E-A7DA-D5D69505808FQ24291265-589A7FBD-FEF6-4833-AA0D-4BC532D66693Q24291989-F1B2BD03-F036-4849-8147-940ADC6DC889Q24292328-3373CDC7-7F2C-465C-A987-9E0CBBE0028EQ24292755-70ADE14E-47AC-4B6C-B3E9-4E0EE775BD80Q24293666-82252582-B1E5-4810-8563-1CDBA032A874Q24293991-29C56493-7FB1-402A-A98E-1CAF5E57AFFAQ24295044-5C0C98BC-2AED-4FA9-9BF5-9EF9E7E4F1FCQ24297181-06C0C8C8-A501-45E9-898C-D24A43B1BB9CQ24298023-CEFB76E3-2549-4430-ADDB-7A16EF27FFCCQ24298357-0240059E-8244-427C-B413-A9B9F5737D3BQ24298717-83AF45E0-16B4-4050-B228-3CC3E500D11CQ24307499-6E66BBB7-80AE-4C30-BE29-42DB1F6D7619Q24310189-D7045FF2-6C48-41D0-9D1A-82308DCFB556Q24311518-85098144-FA79-41B0-B795-DBD861661829Q24312021-00873214-3C5C-4629-8DE5-429BD08039DAQ24315056-3BD86D9B-5D39-473B-A0CA-52ABF208E280Q24318291-EA9BD9B2-47D2-4C3E-8021-1BE271D6CC83Q24337394-51DD7758-9964-4819-9C44-3AD426B72E94Q24338505-3FD4FE2C-2BD7-4236-8182-49C89327A27DQ24536029-2750DA12-4296-45ED-B26A-2EA82BCFE6A2Q24540232-2A305602-EE34-4BC5-AFA6-E68B7746E456Q24546156-D21769D7-9841-456F-9799-D715625D6594Q24554302-18093288-0ACD-4A6A-B80B-A63D65867EA6Q24604009-18B0FB56-EA16-4A6E-9102-581178DB3201Q24607672-1078A7C5-F6C3-43EC-B5F2-4CB571275E17Q26825421-7AC9A113-03E8-4142-BFFE-A64DA43AFA4CQ27650163-306EFBE5-AEC7-41B7-B16E-466674A8655EQ27932745-D8D68B69-D3F7-4F14-B9B9-E5A447439325Q27936253-FD1F11BF-8DA7-4095-94D0-94BD6F3DFB2AQ28115619-2742CD80-2DB1-412D-AC5B-D8A2FBC5BC37Q28116840-636B9F84-B4FD-481F-B54A-16F3A8529759Q28119006-A007B454-B58F-41B6-A25C-AF2DFC8EBC53Q28141883-D376501E-B4B9-4352-B496-AF83CBA86B3EQ28213455-C5B73103-BAA1-403D-BE83-DEFA2D2EC4E0Q28478698-57A9AF2D-A611-4B29-AEC5-A704B0536AC9Q28505590-21A0F9FA-409A-48DE-B9E9-7DCD60BB3061Q28593281-8B568100-EC16-4E3F-B534-C9E1063C5BE1
P2860
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A human telomeric protein
@ast
A human telomeric protein
@en
A human telomeric protein
@en-gb
A human telomeric protein
@nl
type
label
A human telomeric protein
@ast
A human telomeric protein
@en
A human telomeric protein
@en-gb
A human telomeric protein
@nl
prefLabel
A human telomeric protein
@ast
A human telomeric protein
@en
A human telomeric protein
@en-gb
A human telomeric protein
@nl
P2093
P50
P3181
P1433
P1476
A human telomeric protein
@en
P2093
B van Steensel
D Broccoli
P304
P3181
P356
10.1126/SCIENCE.270.5242.1663
P407
P577
1995-12-08T00:00:00Z