A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability
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The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genesReplication Stress: A Lifetime of Epigenetic ChangeInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyNF-κB, the first quarter-century: remarkable progress and outstanding questionsIncreased RPA1 gene dosage affects genomic stability potentially contributing to 17p13.3 duplication syndromeInactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in miceThe histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeatsCHD7 expression predicts survival outcomes in patients with resected pancreatic cancer.Epigenome Maintenance in Response to DNA DamageSystematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.A primer on using pooled shRNA libraries for functional genomic screensChromatin replication and epigenome maintenance.Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damageGeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases.Stress activated protein kinase pathway modulates homologous recombination in fission yeastDefining genome maintenance pathways using functional genomic approachesOvarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription FactorsRepair synthesis step involving ERCC1-XPF participates in DNA repair of the Top1-DNA damage complex.hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress.A whole genome RNAi screen identifies replication stress response genes.Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network.Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis.H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.Identification of proteins at active, stalled, and collapsed replication forks using isolation of proteins on nascent DNA (iPOND) coupled with mass spectrometry.Interferon alpha-inducible protein 6 regulates NRASQ61K-induced melanomagenesis and growthRegulation of Replication Fork Advance and Stability by Nucleosome Assembly.Degradation-linked ubiquitin signal and proteasome are integral components of DNA double strand break repair: New perspectives for anti-cancer therapy.Beyond ATM: the protein kinase landscape of the DNA damage response.Towards systematic functional characterization of cancer genomes.Cyclin K goes with Cdk12 and Cdk13Unraveling DNA damage response-signaling networks through systems approaches.Ewing sarcoma protein: a key player in human cancerRNA splicing: a new player in the DNA damage responseGenotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9.Replication fork reversal in eukaryotes: from dead end to dynamic response.The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability.
P2860
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P2860
A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A genome-wide camptothecin sen ...... required for genomic stability
@ast
A genome-wide camptothecin sen ...... required for genomic stability
@en
A genome-wide camptothecin sen ...... required for genomic stability
@en-gb
A genome-wide camptothecin sen ...... required for genomic stability
@nl
type
label
A genome-wide camptothecin sen ...... required for genomic stability
@ast
A genome-wide camptothecin sen ...... required for genomic stability
@en
A genome-wide camptothecin sen ...... required for genomic stability
@en-gb
A genome-wide camptothecin sen ...... required for genomic stability
@nl
prefLabel
A genome-wide camptothecin sen ...... required for genomic stability
@ast
A genome-wide camptothecin sen ...... required for genomic stability
@en
A genome-wide camptothecin sen ...... required for genomic stability
@en-gb
A genome-wide camptothecin sen ...... required for genomic stability
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
A genome-wide camptothecin sen ...... required for genomic stability
@en
P2093
Alberto Ciccia
Brenda C O'Connell
Britt Adamson
J Wade Harper
John R Lydeard
Mathew E Sowa
Michael Schlabach
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2010.10.022
P407
P577
2010-11-24T00:00:00Z