Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta
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GSK-3β: A Bifunctional Role in Cell Death PathwaysEndoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activityCytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'Regulation of autophagy by cytoplasmic p53Unfolded protein response in a Drosophila model for retinal degenerationAlterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 MutantsModulation of the unfolded protein response by the human hepatitis B virusGSK-3 as potential target for therapeutic intervention in cancerZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53Reciprocal repression between P53 and TCTPPERK Integrates Oncogenic Signaling and Cell Survival During Cancer DevelopmentEndoplasmic reticulum stress stimulates p53 expression through NF-κB activationA monoclonal antibody against p53 cross-reacts with processing bodiesDoxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.GSK-3: Functional Insights from Cell Biology and Animal Models.Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and functionStat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation.Impaired p53 binding to importin: a novel mechanism of cytoplasmic sequestration identified in oxaliplatin-resistant cells.Regulation of NT-PGC-1alpha subcellular localization and function by protein kinase A-dependent modulation of nuclear export by CRM1.Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progressionImmunohistochemical evaluation of inflammatory and proliferative markers in adjacent normal thyroid tissue in patients undergoing total thyroidectomy: results of a preliminary study.Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response.Protein mislocalization: mechanisms, functions and clinical applications in cancer.Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta.GSK3β-dependent phosphorylation alters DNA binding, transactivity and half-life of the transcription factor USF2.Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivoA novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53Genotoxic stress/p53-induced DNAJB9 inhibits the pro-apoptotic function of p53.What Are the bona fide GSK3 Substrates?Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo.The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways.Glycogen synthase kinase 3β inhibitors protect hippocampal neurons from radiation-induced apoptosis by regulating MDM2-p53 pathway.Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferationIn vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activationAneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cellsNuclear accumulation of glycogen synthase kinase-3 during replicative senescence of human fibroblasts.Post-translational modification of p53 in tumorigenesis.
P2860
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P248
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P2860
Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@ast
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en-gb
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@nl
type
label
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@ast
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en-gb
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@nl
prefLabel
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@ast
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en-gb
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@nl
P2093
P2860
P921
P356
P1433
P1476
Endoplasmic reticulum stress i ...... glycogen synthase kinase-3beta
@en
P2093
Akihiko Yoshimura
Ana-Maria Rivas-Estilla
Antonis E Koromilas
Dionissios Baltzis
Maria Hatzoglou
Olivier Pluquet
Shirley Huang
Yoichi Taya
P2860
P304
P356
10.1101/GAD.1165804
P407
P577
2004-02-01T00:00:00Z