about
ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseasesThe Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6pA novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cellsHuman CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase alphaPR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cellsThe regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cellsHuman CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phaseThe human homolog of Saccharomyces cerevisiae CDC45Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosisCell cycle-regulated expression of mammalian CDC6 is dependent on E2F.Cdc6 protein causes premature entry into S phase in a mammalian cell-free system.Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localizationHuman cytomegalovirus infection leads to accumulation of geminin and inhibition of the licensing of cellular DNA replication.Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunitIdentification and characterization of a human protein kinase related to budding yeast Cdc7pMultistep regulation of DNA replication by Cdk phosphorylation of HsCdc6HA95 and LAP2 beta mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replicationCdc6 is regulated by E2F and is essential for DNA replication in mammalian cellsThe essential role of Saccharomyces cerevisiae CDC6 nucleotide-binding site in cell growth, DNA synthesis, and Orc1 association.G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus.In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradationCDC6: from DNA replication to cell cycle checkpoints and oncogenesisSeparate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cellsA potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.Cdc6 chromatin affinity is unaffected by serine-54 phosphorylation, S-phase progression, and overexpression of cyclin A.A CDC6 protein-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor.Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer.Xenopus Cdc6 performs separate functions in initiating DNA replicationActivation of Cdc6 by MyoD is associated with the expansion of quiescent myogenic satellite cells.Active role of a human genomic insert in replication of a yeast artificial chromosome.Identification of the sequence responsible for the nuclear localization of human Cdc6.Cell cycle regulation of human CDC6 protein. Intracellular localization, interaction with the human mcm complex, and CDC2 kinase-mediated hyperphosphorylation.Molecular and genetic aspects of lung cancer.Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle.Control of DNA replication licensing in a cell cycle.Replication licensing--defining the proliferative state?The functional role of Cdc6 in S-G2/M in mammalian cells.
P2860
Q22003912-0A09B478-A30F-457B-B09C-6F07039CDF75Q22008054-4EA583A9-887C-4530-A34A-838019B8AC17Q22010137-9EAF241E-6140-4C30-93A1-25575963836EQ22010642-45314FC7-B30F-43EA-A245-BC2E2396BE85Q22011045-5DC36B66-F2ED-4F36-AA08-EDC42BE8EB26Q24301758-568A1810-E8E2-4018-B371-A7755AFAD163Q24310880-7C242806-26A4-4584-97DB-C3A316AAF2C3Q24313865-72B36C1A-D00C-4B9C-A11B-B539F55174FAQ24515107-50D293DE-EF88-4E04-AD2D-3FB3F281A671Q24522801-E9DA8964-39D9-46CB-99FF-8DB06F2B37C4Q24533451-8B6DC99B-677C-4156-BFCB-394E9CB81A8BQ24533531-4F587B58-28A3-456B-8078-D7AE69B01A86Q24541379-8ECCB8F5-3BA6-4CD4-8763-DB4B67DA1897Q24600785-D01D7CF3-CB83-43CB-B91B-36D91E6133AAQ24643937-3A69CE79-A950-4E34-84CD-16DC09A5CA1EQ24649005-52A24A2F-11B1-4798-99A0-09B8F8056246Q24656841-04AF36CE-5756-4559-8D53-0DFBE6EB6726Q24675954-55370581-673F-48B1-BB94-B7800941BDB4Q24682117-3355C539-7F7A-4471-9424-BD597BD7E3BAQ27931255-7FC284EF-F1BA-4BA5-A0F3-BA9A09C1E010Q27937350-05E007D4-9689-411F-B095-045B6842FA75Q27938355-B5544046-08A0-45E1-86FF-A5DE386B46F7Q28184480-96CD9ABC-19EE-4479-9933-5BBD53E259E2Q28259261-331DC663-87DC-4C0B-9091-92F7560BA6A1Q28348429-E6F20181-85D9-4B66-B5C5-175E9E9F4D5FQ28613373-CE82E02B-C51A-46FA-B0A4-D7AA44EA701CQ30308297-6816848D-8CDE-4978-B5E2-F37EE13BA632Q30312052-FDC2B89A-D58F-4790-860E-727BA7080A94Q30656066-FD387FFD-2E91-48D4-A138-6A421D64F62BQ32107802-FBF0393F-892B-418B-B271-2684500D1831Q33608362-B15C93B1-55E8-4EFD-BBF7-EE6457DE29D9Q33616461-FBD6EF70-8FC9-4298-93F2-34C924B1E137Q33652194-3568BF32-F55E-4488-AC6D-DA2427CD82D0Q33859592-E469B56D-D7AF-46BD-AD7F-BF8302859DE8Q33872351-5F034620-04B2-4227-BB9A-DE3FA9D16931Q33891465-C3B05C29-E3FB-453E-9F10-BC448A6D3F6CQ34114234-4BDAE7CF-3F6E-49C1-AB22-56A8DAFD1B73Q34523944-DB900C78-AA51-4D51-A791-FE794E837C59Q34534992-DD69B052-40D4-40AD-A604-3DD20166768FQ34590385-8A7FCD0E-C3C9-45E1-B45A-5D2ACD73C324
P2860
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A human protein related to yeast Cdc6p
@ast
A human protein related to yeast Cdc6p
@en
A human protein related to yeast Cdc6p
@en-gb
A human protein related to yeast Cdc6p
@nl
type
label
A human protein related to yeast Cdc6p
@ast
A human protein related to yeast Cdc6p
@en
A human protein related to yeast Cdc6p
@en-gb
A human protein related to yeast Cdc6p
@nl
prefLabel
A human protein related to yeast Cdc6p
@ast
A human protein related to yeast Cdc6p
@en
A human protein related to yeast Cdc6p
@en-gb
A human protein related to yeast Cdc6p
@nl
P2860
P356
P1476
A human protein related to yeast Cdc6p
@en
P2093
R S Williams
R V Shohet
P2860
P304
P356
10.1073/PNAS.94.1.142
P407
P577
1997-01-01T00:00:00Z