Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax
about
Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteinsThe nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activatorsIdentification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cellsPTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complexIdentification of the MLL2 complex as a coactivator for estrogen receptor alphaTwo distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivatorsActivating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteinsKnockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localizationSpectrum of MLL2 (ALR) mutations in 110 cases of Kabuki syndromeExome sequencing identifies MLL2 mutations as a cause of Kabuki syndromeKabuki syndrome: clinical and molecular characteristicsThe structure of the FYR domain of transforming growth factor beta regulator 1Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone MethyltransferasesTargeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase ComplexesDe novo mutations in MLL cause Wiedemann-Steiner syndrome.The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex.Systematic identification of novel protein domain families associated with nuclear functions.Analysis of the coding genome of diffuse large B-cell lymphomaUnmasking Kabuki syndrome.Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.Mutant alleles of the Drosophila trithorax gene produce common and unusual homeotic and other developmental phenotypes.Analysis of 148 kb of genomic DNA around the wnt1 locus of Fugu rubripes.Mutation spectrum of MLL2 in a cohort of Kabuki syndrome patients.MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progressionHistone recognition and nuclear receptor co-activator functions of Drosophila cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathwaysTranscription factor Ap2delta associates with Ash2l and ALR, a trithorax family histone methyltransferase, to activate Hoxc8 transcriptionConstruction and application of a zebrafish array comparative genomic hybridization platformEpigenetics, autism spectrum, and neurodevelopmental disorders.Histone H3 lysine 4 (H3K4) methylation in development and differentiationBinding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.Spatial localization of genes determined by intranuclear DNA fragmentation with the fusion proteins lamin KRED and histone KRED und visible light.Histone H3 lysine 4 methyltransferase KMT2D.Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors.The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.
P2860
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P2860
Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Structure and expression patte ...... ia and to Drosophila trithorax
@ast
Structure and expression patte ...... ia and to Drosophila trithorax
@en
Structure and expression patte ...... ia and to Drosophila trithorax
@en-gb
Structure and expression patte ...... ia and to Drosophila trithorax
@nl
type
label
Structure and expression patte ...... ia and to Drosophila trithorax
@ast
Structure and expression patte ...... ia and to Drosophila trithorax
@en
Structure and expression patte ...... ia and to Drosophila trithorax
@en-gb
Structure and expression patte ...... ia and to Drosophila trithorax
@nl
prefLabel
Structure and expression patte ...... ia and to Drosophila trithorax
@ast
Structure and expression patte ...... ia and to Drosophila trithorax
@en
Structure and expression patte ...... ia and to Drosophila trithorax
@en-gb
Structure and expression patte ...... ia and to Drosophila trithorax
@nl
P2093
P921
P356
P1433
P1476
Structure and expression patte ...... ia and to Drosophila trithorax
@en
P2093
A B Zhadanov
F Bullrich
R Rallapalli
P2888
P304
P356
10.1038/SJ.ONC.1201211
P407
P577
1997-07-31T00:00:00Z
P5875
P6179
1028986038