Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
about
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalThe program of androgen-responsive genes in neoplastic prostate epithelium.The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophagesTranslocation T(4;14)(p16.3;q32) is a recurrent genetic lesion in primary amyloidosisExpression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomasClassification between normal and tumor tissues based on the pair-wise gene expression ratioWWOX, the common chromosomal fragile site, FRA16D, cancer geneA mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 miceRegulation of c-maf gene expression by Pax6 in cultured cellsAn integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma.In multiple myeloma, 14q32 translocations are nonrandom chromosomal fusions driving high expression levels of the respective partner genes.Sequence and insertion sites of murine melanoma-associated retrovirus.Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation.Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma.WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.Transcriptional factors, Mafs and their biological rolesGenetics of multiple myeloma: another heterogeneity level?Pulverulent cataract with variably associated microcornea and iris coloboma in a MAF mutation family.Immunohistochemical analysis of cyclin D1 shows deregulated expression in multiple myeloma with the t(11;14).The ubiquitin-proteasomal system is critical for multiple myeloma: implications in drug discoveryPlasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma.Hodgkin's lymphoma associated T-cells exhibit a transcription factor profile consistent with distinct lymphoid compartmentsAPOBEC family mutational signatures are associated with poor prognosis translocations in multiple myelomaWhole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tidesIn multiple myeloma, bone-marrow lymphocytes harboring the same chromosomal abnormalities as autologous plasma cells predict poor survivalGenetic events in the pathogenesis of multiple myeloma.The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.Relationship between elevated immunoglobulin free light chain and the presence of IgH translocations in multiple myelomaMafA is a Key Molecule in Glucose and Energy Balance in the Central Nervous System and Peripheral OrgansCharacterization of c-Maf transcription factor in normal and neoplastic hematolymphoid tissue and its relevance in plasma cell neoplasiaSecondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors.Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myelomaDistinct genomic aberrations associated with ERG rearranged prostate cancerGenomics in multiple myeloma.Multiple functions of Maf in the regulation of cellular development and differentiation.Characterization of MYC translocations in multiple myeloma cell lines.Genetic aberrations and survival in plasma cell leukemiaProteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia.Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models.
P2860
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P2860
Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@ast
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en-gb
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@nl
type
label
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@ast
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en-gb
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@nl
prefLabel
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@ast
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en-gb
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@nl
P2093
P1433
P1476
Frequent dysregulation of the ...... n Ig locus in multiple myeloma
@en
P2093
Bergsagel PL
Martelli ML
Shonukan OO
P304
P407
P577
1998-06-01T00:00:00Z